Title |
GSTM1 GENE POLYMORPHISMS AND RISK OF BREAST CANCER IN J&K STATE |
| Genetics Vol:9 Iss:4 (2017-04-28) : 263-265 |
Authors |
RAVI SHARMA, JYOTDEEP KOUR RAINA, TARIQ AZAD, PARVINDER KUMAR, RAKESH KUMAR PANJALIYA |
Published on |
28 Apr 2017 Pages : 263-265 Article Id : BIA0003598 Views : 956 Downloads : 674 |
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Abstract |
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Homozygous deletion of GSTM1 gene affects carcinogenic detoxification and promotes tumorogenesis in breast tissue. The present study was aimed to evaluate the frequency of GSTM1 genotypes/alleles and its association in risk of breast cancer in North Indian population of Jammu (Jammu and Kashmir). A total of 60 confirmed breast cancer patients and 90 healthy unrelated controls were enrolled in this study. Genotyping analysis was performed by Polymerase Chain Reaction (PCR) based methods and odds ratios (ORs) were calculated to know the strength of association. The frequencies of null and positive GSTM1 alleles/genotypes were 0.12/11.67% and 0.88/88.33% in patients whereas in controls it was 0.18/17.78% and 0.82/82.22% respectively. We did not found the association of GSTM1 null genotype towards risk of breast cancer [OR=0.61, 95% CI (0.23-1.59), p=0.6]. The present study is in support of lack of association of null GSTM1 genotype and risk of breast cancer in population of Jammu.
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Title |
STUDY OF GROWTH AND YIELD VARIATION OF CHICKPEA GENOTYPES UNDER MOISTURE STRESS CONDITION (PHYSIOLOGICAL BASIS OF GROWTH AND YIELD VARIATION OF CHICKPEA GENOTYPES UNDER MOISTURE STRESS CONDITION) |
| Genetics Vol:9 Iss:4 (2017-04-28) : 266-270 |
Authors |
R.O. BRAHMANE, R.W. BHARUD, D.V. DESHMUKH |
Published on |
28 Apr 2017 Pages : 266-270 Article Id : BIA0003630 Views : 964 Downloads : 721 |
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Six chickpea genotypes were evaluated for growth and yield variation under moisture stress condition during Rabi-2011 and 2012. Separate experiments were conducted under rainout shelter condition for moisture stress, mild stress and non-stress in split plot design with three replications. Observations were recorded on moisture status at 15 days interval. The per cent available moisture content was reduced and severity duration frequency (SDF) was increased with the advancing age of the crop. The initiation of flowering and 50% flowering was unaffected however the maturity period was declined due to moisture stress and mild stress condition in all the genotypes. The genotypes Vijay and Digvijay were earlier, whereas, PG-5 and Chaffa were late for days to initiation of flowering, 50% flowering and maturity under all the conditions. Vijay and Digvijay maintained higher dry matter accumulation in component parts of plant under different growing conditions at various stages of growth. The bold seed size genotypes Digvijay and Vishal and medium bold Vijay were promising in respect of yield and yield contributing characters under different growing conditions. Therefore, these genotypes might be considered as drought tolerant types.
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