INSECT NEUROPEPTIDES AND G-PROTEIN COUPLED RECEPTORS: NEXT GENERATION PESTICIDES

PRIYANKABEN PATEL¹*, DILIP SISODIYA², RAMJI PARMAR^3
1Department of Plant Pathology, B. A. College of Agriculture, Anand Agricultural University, Anand 388 110, Gujarat, India
²Department of Agricultural Entomology, B. A. College of Agriculture, Anand Agricultural University, Anand 388 110, Gujarat, India
³Department of Plant Pathology, B. A. College of Agriculture, Anand Agricultural University, Anand 388 110, Gujarat, India
* Corresponding Author : virrajjilupatel@gmail.com

Received : 02-07-2021     Accepted : 27-07-2021     Published : 30-07-2021
Volume : 13     Issue : 7       Pages : 10825 - 10828
Int J Agr Sci 13.7 (2021):10825-10828

Keywords : Neuropeptides, G Protein Coupled Receptors (GPCRs), pesticides, analogues, insecticide, Juvenile Hormone (JH), Diuretic Hormone (DH)
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Plant Pathology, B. A. College of Agriculture, Anand Agricultural University, Anand 388 110, Gujarat, India. Authors are also thankful to Department of Agricultural Entomology, B. A. College of Agriculture, Anand Agricultural University, Anand 388 110, Gujarat, India
Author Contribution : All authors equally contributed

Farmers choose chemical insecticides due to its rapid knockdown effect on insect-pests. Ultimately, there is increased incidence of pest resurgence, appearance of resistant pest species and residual problem of pesticides. According to the demand of present situation, one such ecofriendly approach is use of insect neuropeptides and their receptors. Neuropeptides initiate their biological effects by binding to different receptors like G-Protein Coupled Receptors (GPCRs). The insect’s major processes viz., behavioural and physiological are being modulated by neuropeptides and GPCRs. In insects, various processes like growth and development, reproduction, energy metabolism and behavioural activities like mating, oviposition, etc. are controlled by neuropeptides and GPCRs. Neuropeptides have been categorized into different groups according to their function such as Diuretic hormone (DH), Adipokinetic hormone (AKH), Eclosion hormone (EH), Pheromone Biosynthesis Activating Neuropeptides (PBAN), Allatotropins (ATT) and Allostatins (AST). Neuropeptides can be used in pest control strategy by developing neuropeptide-based insecticides which are target specific and ecofriendly

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