DETECTION OF MRK D GENE AND ANTIBIOGRAM OF BIOFILM PRODUCING KLEBSIELLA PNEUMONIAE FROM VARIOUS INDWELLING DEVICES

K. KAUR¹*, A.K. HEYAR², P.K. GILL^3
1Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, 151101, Punjab, India
²Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, 151101, Punjab, India
³Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, 151101, Punjab, India
* Corresponding Author : kamaldeepkaur_06@yahoo.in

Received : 01-07-2020     Accepted : 13-07-2020     Published : 30-07-2020
Volume : 12     Issue : 7       Pages : 1862 - 1866
Int J Microbiol Res 12.7 (2020):1862-1866

Keywords : Biofilm, Fimbrae, Indwelling devices, MDR, MrkD
Academic Editor : Ranabijuli S., Dr Carlos Aa Chagas
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, 151101, Punjab, India
Author Contribution : All authors equally contributed

Indwelling medical devices are most vulnerable to microbial colonization. As a result, Device Related Infection has emerged as a new challenge in the medical research. In the present investigation total 414 multiple drug resistance gram negative bacilli were isolated in which 27.5% were associated with indwelling medical devices. 35% found to be K. pneumoniae isolates out of which 23 were detected as biofilm producing. Tracheostomy tips showed the presence of maximum number of K. pneumoniae. Highest sensitivity in biofilm producing strains was observed in Colistin followed by Tigecycline. Further, MrkD gene was also detected which is responsible for biofilm formation.

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