ISSN : 0975-5276
EISSN : 0975-9174
A.C. SAJJAN1, V. PRAVEEN KUMAR2*
1Department of Microbiology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, 505001, Kaloji Narayana Rao University of Health Sciences, Warangal, 506007, Telangana, India
2Department of Microbiology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, 505001, Kaloji Narayana Rao University of Health Sciences, Warangal, 506007, Telangana, India
* Corresponding Author : vpraveenkumar4@gmail.com
Received : 01-10-2019 Accepted : 26-10-2019 Published : 30-10-2019
Volume : 11 Issue : 10 Pages : 1720 - 1723
Int J Microbiol Res 11.10 (2019):1720-1723
Keywords : Dengue, Chikungunya, NS1 Antigen, ELISA, Immunochromatography
Academic Editor : Hamid, Takemi Otsuki, Dr M.G. Rathod
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, 505001, Kaloji Narayana Rao University of Health Sciences, Warangal, 506007, Telangana, India
Author Contribution : All authors equally contributed
Arthropod-borne viruses are a major burden on the health-care system worldwide. Dengue and Chikungunya RNA viral infections are the highly spreading arboviral infections. The current study was conducted at Chalmeda Ananda Rao Institute of Medical Sciences, Karimnagar, Telangana, from August 2018 to September 2019. A total of 3652 serum samples were received from dengue suspected cases and 468 samples were received from suspected cases of Chickungunya and 174 samples were tested for both dengue and chikungunya Co-infection. Of the 3652 serum samples received, 631, were positive for dengue mono infection, of which 427 (67.6%) were males and 204 (32.3%) females. Among the 468 samples for chikungunya test, 29 were positive for chikungunya, of which 21 (72.4%) were from males and 8(27.5%) from females. Patients' age ranged between 22 to 56 years. Only 174 samples were tested for coinfection of dengue and chikungunya, where 6 (3.4%) of them were positive for co- infections of which predominant were observed in male patients 5(83.3%) and female 1(16.6%). Clinical presentation of the patients showed that fever (100%) is a common symptom in all the cases, headache was the most common symptom in dengue and chikungunya coinfection. Arthralgia was predominantly observed among chikungunya patients 86.20%, whereas 13.94% in dengue and 83.33% in co-infection. Myalgia was seen more prevalent among dual infection patients 83.33% and dengue patients (41.67%) compared to chikungunya patients 34.48%. Management of dengue and chikungunya viral infections are totally based on the supportive treatment. We investigated the changing trends of epidemiology of dengue clinical spectrum and prevalence of chikungunya and their coinfection rates.
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