STUDY OF ANTIMICROBIAL RESISTANCE PATTERN OF NON-FERMENTERS IN A MEDICAL COLLEGE HOSPITAL OF WESTERN INDIA

K.J. PATEL¹, SUMEETA SONI²*, ANOKHI GOSWAMI³, NRUTI GANDHI⁴, PRIYA PATEL⁵, YESHA SUTHAR^6
1Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
²Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
³Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
⁴Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
⁵Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
⁶Department of Microbiology, B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
* Corresponding Author : drsumeetasoni@gmail.com

Received : 29-08-2018     Accepted : 26-09-2018     Published : 30-09-2018
Volume : 10     Issue : 9       Pages : 1367 - 1369
Int J Microbiol Res 10.9 (2018):1367-1369

Keywords : MBL, non-fermenter, Pseudomonas spp., Acinetobacter spp
Conflict of Interest : None declared
Acknowledgements/Funding : Author thankful to B.J. Medical College, Ahmedabad, 380016, Gujarat University, Navrangpura, Ahmedabad, 380009, Gujarat India
Author Contribution : All author equally contributed

Background & Objective: The antimicrobial resistance to most of the antimicrobial agent is very commonly seen among non-fermenters. Recently, New Delhi metallo beta-lactamase(NDM) has emerged as a novel carbapenemase8.Carbapenem resistance is a major public health concern. Emergence of MBL producing Non-fermenters is alarming and reflects excessive use of carbapenams. Results: Out of 1932 non-fermenter isolates from various clinical specimens. 1393(72%) were Pseudomonas spp. and 539(28%) were Acinetobacter spp. Interpretation & Conclusion: Antimicrobial resistance to most of the antimicrobial agent which includes MBL in non-fermenter is becoming a therapeutic challenge. Only few drugs such as Polymyxin-B, Colistin and Tigecycline are suggested as possible effective treatment choices which are expensive and most of the times unavailable. Therefore, rapid detection of mechanism of resistance necessary to modify therapy & to initiate effective infection control to prevent their dissemination.

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