ANTIMICROBIAL STUDIES OF SOME NOVEL ORGANOBISMUTH COMPOUNDS

PRAMILA GUPTA¹, PREETI RANI², RAVI KANT³*
¹Department of Chemistry, Mewar University, Chittorgarh, 312901, Rajasthan, India
²Department of Chemistry, Mewar University, Chittorgarh, 312901, Rajasthan, India
³Department of Chemistry, Mewar University, Chittorgarh, 312901, Rajasthan, India
* Corresponding Author : drravikant78@gmail.com

Received : 20-03-2018     Accepted : 25-03-2018     Published : 30-03-2018
Volume : 10     Issue : 3       Pages : 1083 - 1085
Int J Microbiol Res 10.3 (2018):1083-1085
DOI : http://dx.doi.org/10.9735/0975-5276.10.3.1083-1085

Keywords : Organobismuth, isatin, antibacterial, antifungal
Conflict of Interest : None declared
Acknowledgements/Funding : Author thankful to Department of Chemistry, Mewar University, Chittorgarh, 312901, Rajasthan
Author Contribution : All author equally contributed

The present manuscript deals with the synthesis and characterization of some novel organobismuth derivatives of isatin for their antimicrobial activity. These compounds were synthesized by the reported method and characterized with the help of M.P., elemental, I.R spectral analysis along with their efficacy against pathogenic bacterial and fungal strains. It was found that the compounds exhibit higher activity than the standard drug for bactericidal and fungicidal activity.

1. Jada S.K. & Jayakumar K. (2012) Inter J Med Clin Research, 3,154-160.
2. Guo Z. and Sadler P.J. (2000) Adv. Inorg. Chem., 49, 183.
3. Clarke M.J., Zhu F. and Frasca D.R. (1999) Chem. Rev, 99, 2511.
4. Gielen M. (1988) Editor Metal Based Antitumor Drugs, freund Publishing House Ltd. London.
5. Chauhan V.S., Tiwari V.K., Shukla S.K., Rani S., Mishra S.N., Ravi Kant and Tewari I.C. (2009) Inter. Jour. of Biotech. Resear., 2(1), 67-71,.
6. Tiwari V. K., Shailendra K. Shukla, Chauhan V. S., Ravi Kant, Sushma Rani and Tewari I.C. (2010) Inter. Jour. of Pharma. Analy., 2(1), 09-14.
7. Deepti Mani Tripathi, Amresh G. and Ravi Kant (2011) Jour. of Medi. Chem. Letters, 1(1), 01-06.
8. D.M. Tripathi, Amresh G. and Ravi Kant (2012) Inter. Jour. of Chem. Resear, 4(1), 110-113.
9. Soni K.K., Kumar Alok and Kant R. (2015) Inter. Jour. of Chem. Resear, 7(1), 159-163.
10. Soni K.K., Kumar Alok and Kant R. (2016) Inter. Jour. of Chem. Resear., 8(1), 168-172.
11. Stratton C.W., Warner R.R., Coudron P.E. and Lilly N.A. (1999) Antimicrob. Agents. Chemother, 43, 659-666.
12. Tyagi S., Singh N., Singh S.M. and Singh U.P. (2004) Synth. React. Inorg. Met.-Org. Chem., 34, 573-591.
13. Kant R., Singhal K., Shukla S.K., Chandrasekhar K., Saxena A.K., Ranjan A. and Raj P. (2008) Phosphorus, Sulfur and Silicon,183, 2029-2039.
14. Kant R., Amresh G., Chandrashekar K. and Anil K.K.S. (2008) Phosphorus, Sulfur and Silicon, 183, 1410-1419.