COMPARISON OF ADAPTIVE CHANGES IN THE EXPRESSION OF SELECTED GENES BETWEEN AN ACTIVE AND FORMER SPEED SKATER – A CASE STUDY

DANUTA DWORAKOWSKA¹*, PIOTR SOWA², PATRYK FLADER³, JACEK WILCZYNSKI⁴, WANDA PILCH^5
1Gdansk University of Physical Education and Sport, Gdansk, Poland
²Gdansk University of Physical Education and Sport, Gdansk, Poland
³Gdansk University of Physical Education and Sport, Gdansk, Poland
⁴Jan Kochanowski University in Kielce, Faculty of Medicine and Health Sciences, Kielce, Poland
⁵University of Physical Education in Krakow, Department of Biochemistry and Basics of Cosmetology, Faculty of Cosmetology, Krakow, Poland
* Corresponding Author : danuta.dworakowska@gmail.com

Received : 14-11-2017     Accepted : 21-11-2017     Published : 28-12-2017
Volume : 9     Issue : 11       Pages : 314 - 317
Genetics 9.11 (2017):314-317

Keywords : adaptive changes, expression of IL6 and IL10 genes, physical fitness
Academic Editor : Chruscinski Grzegorz, Nijole Jascaniniene
Conflict of Interest : None declared
Acknowledgements/Funding : This study was financing by the Gdansk University of Physical Education and Sport from the founds from Polish Ministry of Science 2016. The authors of this work would like to thank Dr. Malgorzata Zychowska for her assistance in performing genetic markings and interpreting the results
Author Contribution : All author equally contributed (DD – study design, writtining the article, performance of the experiment; PS - performance of the experiment, statistical analysis, PF – genetics research, data collection; JW. – literature search, supervision).

Adaptive changes to exercise include, inter alia, the level of IL6 and IL10expression. The aim of the study was to compare adaptation to exercise in the expression of the IL6 and IL10 genes in peripheral blood leukocytes between an active and former speed skater. The two-year period after ending the professional career resulted in differences in anaerobic capacity, and consequently, significantly lower results in exercise tests by the former athlete (difference in maximum power of 1.46 W/kg, time to attain MAP 0.14; VO2max at the average population level). The resting-state and post-exercise expression levels of the tested genes in the former athlete was lower than that of the active athlete, and there was no increased IL10 expression immediately after the test (2^0.2 of baseline after WAnT and 2^0.5 after exercise until refusal in the former athlete). Based on analysis of gene expression results in response to laboratory tests, it was found that 2 years of training interruption resulted in the reduction of adaptive changes to intense physical exercise.

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