PREVALENCE, CO-MORBIDITY FACTORS, CHARACTERIZATION AND ANTIMICROBIAL RESISTANCE PATTERN OF ISOLATES ASSOCIATED WITH BLOOD STREAM INFECTION

KATHERINE JOSEPH¹*, K.K. AMEENA², K.S. SONIYA^3
1Department of Microbiology, MES Medical College, Perintalmanna, Kerala University of Health Science, Thrissur, 680596, Kerala
²Department of Microbiology, MES Medical College, Perintalmanna, Kerala University of Health Science, Thrissur, 680596, Kerala
³Department of Microbiology, MES Medical College, Perintalmanna, Kerala University of Health Science, Thrissur, 680596, Kerala
* Corresponding Author : katherinejc17@gmail.com

Received : 29-03-2017     Accepted : 01-04-2017     Published : 28-04-2017
Volume : 9     Issue : 4       Pages : 884 - 887
Int J Microbiol Res 9.4 (2017):884-887

Keywords : Blood stream infection, Co-morbidity factors, Characterization, Antibiotic resistance, MRSA
Academic Editor : Dr Vinod Kumar Singh, Senouci-rezkallah Khadidja, Katta Prashanth Kumar
Conflict of Interest : None declared
Acknowledgements/Funding : Author are thankful to Department of Microbiology, MES Medical College, Perintalmanna, Kerala University of Health Science, Thrissur, 680596, Kerala
Author Contribution : All authors equally contributed

Background: Blood stream infection (BSI) remains one of the important causes of morbidity and mortality throughout the world. Aim: To study the prevalence, co-morbidity factors, characterization and antimicrobial resistance pattern of isolates associated with blood stream infection. Materials and Methods: A retrospective study carried out on blood culture samples and catheter tip cultures in a tertiary care teaching hospital from January 2016 to December 2016 according to standard protocol. Data Analysis was done by using WHO NET ANTIBIOTIC RESISTANCE SURVEILLANCE SOFTWARE. Result: A total of 3269 blood samples were processed, out of which 327 showed growths of organisms. The most vulnerable age group was above 70 years where the incidence was 22.1% and the lowest incidence was observed among age group 1 to 10 years (3.4%). Respiratory infection was the predominant co-morbidity factor. Among the isolates, Gram positive bacteria accounted for 54. 9 % with Staphylococcus aureus topping the list (39.1%) and 43.3 % of were MRSA; all the strains showed 0% resistance to vancomycin and linezolid. E. coli was the predominant Gram negative bacteria (13.3%) followed by Acinetobacter (8.2%). Conclusion: Blood stream infection (BSI) is one of the most important causes of morbidity and mortality. S. aureus and E. coli are the most common organisms isolated in this study. Increasing rates of antimicrobial resistance pose a great problem in treating these infections leading to high morbidity and mortality.

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