H1N1 IN PREGNANCY- AN OVERVIEW OF CASES IN PATIENTS ADMITTED AT A TERTIARY CARE HOSPITAL

K.K. MEHTA¹*, M.M. VEGAD², S.T. SONI³, C.S. DABHI⁴, V.S. LAVANYAADEVI⁵, M.R. MARADIA^6
1Resident Doctor, Department of Microbiology, B.J. Medical College, Ahmedabad, India
²Professor & Head of Department, Department of Microbiology, B.J. Medical College, Ahmedabad, India
³Associate Professor, Department of Microbiology, B.J. Medical College, Ahmedabad, India
⁴Resident Doctor, Department of Microbiology, B.J. Medical College, Ahmedabad, India
⁵Resident Doctor, Department of Microbiology, B.J. Medical College, Ahmedabad, India
⁶Resident Doctor, Department of Microbiology, B.J. Medical College, Ahmedabad, India
* Corresponding Author : kanksha.km@gmail.com

Received : 11-07-2015     Accepted : 21-10-2015     Published : 15-11-2015
Volume : 7     Issue : 5       Pages : 683 - 685
Int J Microbiol Res 7.5 (2015):683-685

Keywords : H1N1 infection, Pregnancy, rRT PCR
Academic Editor : Dr Prof Hansa Goswami, Dr Pranay Shah, Marta Canuti, Sukhramani Prakash S
Conflict of Interest : None declared
Acknowledgements/Funding : This study was supported by Department of Microbiology, B.J.Medical College, Ahmedabad. We wish to show our gratitude to the following for provision of data. Department of Microbiology, Department of Obstetrics & Gynecology, B.J.Medical College, Ahmedabad

Background & Objectives: The Influenza A H1N1 is a novel strain of the influenza A virus. The risk of morbidity from H1N1 is higher among pregnant women, specifically in second and third trimester. Pregnant women, because of their altered immunity and physiological adaptations, are at higher risk of developing pulmonary complications. This study was done to observe pattern and severity of H1N1 cases in pregnant women. Objective was to know the prevalence of H1N1 cases and risk factors associated with it in pregnancy. Methods: This study was conducted over a period of 3 months from January to March 2015. The following inclusion criteria were used: Pregnancy confirmed via beta human chorionic gonadotropin test or ultrasound, Suspected or confirmed infection with H1N1 virus, Infection requiring hospitalisation, Admitted at Civil Hospital, Ahmedabad. Results: Out of 39-suspected antenatal women, 29 were tested positive for pandemic novel H1N1. (74.3%) out of which 27 patients had normal delivery (93.1%). One case was emergency caesarean section (3.4%); one case was of a preterm delivery (3.4%). With reference to maternal outcome, 15 women survived (51.7%) and 14 women died (48.3%). Interpretation &Conclusion: H1N1 infection in pregnancy may lead to fatal outcome both maternally and perinatally. Proper antenatal management as per symptoms and early diagnosis may help reducing mortality.