SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW AMIDES OF 5-SULPHOSALICYLIC ACID

Mishra Anjali¹, Singh R.K.², Singh S.³, Mishra A.⁴, Kumar M.⁵, Kant Ravi⁶, Thakur R.S.⁷*
¹Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
²Department of Applied Chemistry, Prabhat Engineering College, Kanpur
³Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
⁴Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
⁵Department of Applied Chemistry, Vidya Bhawan Engineering College, Kanpur
⁶Department of Applied Chemistry, Prabhat Engineering College, Kanpur
⁷Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
* Corresponding Author : profrsthakur@gmail.com

Received : -     Accepted : -     Published : 21-12-2009
Volume : 1     Issue : 2       Pages : 1 - 3
Int J Pharmaceut Anal 1.2 (2009):1-3
DOI : http://dx.doi.org/10.9735/0975-3079.1.2.1-3

Keywords : 5-Sulphosalicylic acid, amines, antifungal, antibacterial and insecticidal activities
Conflict of Interest : None declared
Acknowledgements/Funding : The authors are highly thankful to the Director CDRI & NBRI Lucknow for spectral and elemental analysis along with antimicrobial studies.The authors are also thankful to Principal,D.B.S.P.G.College, Kanpur for providing necessary laboratory facility

Some new amides of 5-Sulphosalicylic acid were synthesized by the reaction of suitable amines with 5-sulphosalicylic acid in 2:1 ratio. The compounds are novel and first time screened for their complete biological evaluation along with general characterization with the help of elemental and IR spectral analysis. These compounds showed higher to moderate biological activity against different pathogenic microbial strains.

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