Increasing emergence of antibacterial resistance mainly in uropathogens: southeast part of India

Bhargavi P.S.1, Gopala Rao T.V.2, Mukkanti K.3, Dinesh Kumar B.4, Krishna T.P.5
1Montessori Mahila Kalasala, Vijayawada, Andhra Pradesh, India
2Gandhi Institute of Biological Sciences, Gunpur, Orissa, India
3Department of Environmental Sciences, J.N.T.U, Kukatpally, Hyderabad, Andhra Pradesh, India
4NIN, Hyderabad, Andhra Pradesh, India
5NIN, Hyderabad, Andhra Pradesh, India

Received : -     Accepted : -     Published : 15-06-2010
Volume : 2     Issue : 1       Pages : 1 - 6
Int J Microbiol Res 2.1 (2010):1-6
DOI : http://dx.doi.org/10.9735/0975-5276.2.1.1-6

Keywords : antibiotics, resistance, biological samples, gram negative and gram positive organisms
Conflict of Interest : None declared

Cite - MLA : Bhargavi P.S., et al "Increasing emergence of antibacterial resistance mainly in uropathogens: southeast part of India." International Journal of Microbiology Research 2.1 (2010):1-6. http://dx.doi.org/10.9735/0975-5276.2.1.1-6

Cite - APA : Bhargavi P.S., Gopala Rao T.V., Mukkanti K., Dinesh Kumar B., Krishna T.P. (2010). Increasing emergence of antibacterial resistance mainly in uropathogens: southeast part of India. International Journal of Microbiology Research, 2 (1), 1-6. http://dx.doi.org/10.9735/0975-5276.2.1.1-6

Cite - Chicago : Bhargavi P.S., Gopala Rao T.V., Mukkanti K., Dinesh Kumar B., and Krishna T.P. "Increasing emergence of antibacterial resistance mainly in uropathogens: southeast part of India." International Journal of Microbiology Research 2, no. 1 (2010):1-6. http://dx.doi.org/10.9735/0975-5276.2.1.1-6

Copyright : © 2010, Bhargavi P.S., et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

The existence of large concern over the increasing resistance to antibiotics for clinically important pathogens which cause varied number of diseases has led to monitor the prevailing resistance pattern of microbes in a study which was carried out in the city of Vijayawada in Andhra Pradesh. In this study, the data of urinary isolates which showed antibiotic resistance patterns were collected from government hospital, multispecialty hospital and a private laboratory. Total 1424 retrospective samples were collected and evaluated for antimicrobial resistance. The samples 676 (47.5%) were positive and 748 (52.5%) were negative to the infection. The antibiotics which showed higher rate of resistance by the urinary isolates were Amoxicillin, Ciprofloxacin, Co-Trimoxazole, Norfloxacin, Nalidixic acid. In contrast, organisms showed susceptibility to Amikacin and then to Azithromycin. Among the gram negative organisms, Escherichia coli was resistance to Amoxicillin (100%), Nalidixic Acid (92.6%), while Klebsiella pneumoniae was found resistance to Amoxicillin (96.3%), Gentamycin (83.3%), Pseudomonas aeruginosa was highly resistance (100%) to Amoxicillin, Ciprofloxacin, Norfloxacin, Nalidixic acid and Co-trimoxazole. Under gram positive organisms Staphylococcus aureus showed resistance to Amoxicillin (72.7%), Nalidixic acid (66.7%) and Enterococcus faecalis was resistance to Nalidixic acid (88.9%) and Norfloxacin (83.3%).

References

[1] Kenneth Todar (2008) In a book Todar’s online text book of bacteriology. http://www.textbookof bacteriology.net/resantimicrobial_4.html  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[2] About Antibiotic resistance. http://www.tufts.edu/med/apua/Q&A/Q& A_AR.html  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[3] Kamini W. (2006) Emerging Problem of Antimicrobial Resistance in Developing Countries: Interwining Socio economic Issues. Regional Health Forum WHO South- East Asia Region, 7( 1), 2006  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[4] Vibha V. Broad spectrum drug rule India. http://www.downearth.org.in/full6  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[5] Rao B.L.N., Gowal D., Chaturvedi A.P., Jayasheela M., and Agarwal P. (1987) Indian J Med Microbiol. 7, 21-2  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[6] Khurana S., Taneja N., Sharma M. (2002) Indian J Med Res., 116, 145-149  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[7] Gupta V., Yadav A. and Joshi R.M. (2002) Indian J Med Microbiol. 20, 96-98  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[8] Gales A.C., Sader H.S., Jones, R.N. (2002) Diagn. Microbial Infect. Dis. 44, 289- 299  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[9] Bajaj J.K., Karyokart R.P., Kulkarni J.D. and Deshmukh A.B. (1999) J. Commun. Dis. 31, 181-184  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[10] Younis N., Quol K., Momani T, Awaisheh F.A. and Kayed D.A. (2009) J. Nepal Med. Assoc., 48(173): 14-19.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[11] Abdulrahman A. K., Kumar A. and Dass S.M. (2004) Saudi J. Kidney Dis Trans.15(2), 135-139  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[12] Ahmad S. and Ahmad F. (1995) Bangladesh Med. Res. Coun. Bull.. 21 (3): 95 – 98  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[13] Fluit A.C., Mark E., Jones E., Schmitz,F.J., Acar J. and Gupta R. (2000) Antonie van Leeuwenhoek 77: 147-152  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[14] Schito G.C., Chezzi C., Nicoletti G., Moreddu M., Arcangeletti M.C., Stefani S., Albini E., Bono G.P.D. (1992) Infect. 20 (4). 291  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[15] Movahedian A.H., Mosayebi Z., Moniri S. (2007) J. Infect. Dis. Antimicrob. Agents. 24, 7-11.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[16] Manzoor S., Gash K. and Rukhsana B.A. (2004) Ind. J. for the Practising Doc.1, (1), 23-27  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[17] Priya P., Khurana R. and George J. (2002) Indian J. Pharma., 34; 278-280  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[18] Mohammed A., Mohammed S., Asad and Khan U. (2007) Ind. Annals of Clin. Microbiol. & Antimicrob., 6:4-6  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[19] Hasan A.S., Nair D., Kaur J., Baweja G., and Deb P. (2007) J Ayub Med Coll Abbottabad ., 19 (1). 21-24.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[20] Yengkokpam C., Ingudam D., Yenngkokpam I.S. and Jha B.K. (2007) Nepal Med. Coll. J., 9 (3): 170-172  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[21] Jha N. and Bapat S.K. (2005) Khatmandu Univ. Med. J., 3 No.2, Issue 10, 123- 129  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[22] Elliot T.S., Shelton A. and Greenwood D. (1987) J Med Microbiol., 23:83-88  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[23] Shobha R., Gupta R. and Gaheer R. (2000) Indian J Med Sci., 54:388-94  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[24] Supriya S., Suresh T., Jalgaonkar V., Ahamad S. and Hassani U. (2008) Indian J Med Res 120, 553-556.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus