Oncogenomics: Clinical pathogenesis approach

Gupta G.1, Gupta N.2, Trivedi S.3, Patil P.4, Gupta M.5, Jhadav A.6, Vamsi K.K.7, Khairnar Y.8, Boraste A.9, Mujapara A.K.10, Joshi B.11
1S.D.S.M. College Palghar, Mumbai
2Sindhu Mahavidyalaya Panchpaoli Nagpur
3V.V.P. Engineering College, Rajkot, Gujrat
4Dr. D. Y. Patil ACS College, Pimpri, Pune
5Sindhu Mahavidyalaya Panchpaoli Nagpur
6Padmashree Dr. D.Y. Patil University, Navi Mumbai, 400614, India
7Rai foundations College CBD Belapur Navi Mumbai
8Padmashree Dr. D.Y. Patil University, Navi Mumbai, 400614, India
9Padmashree Dr. D.Y. Patil University, Navi Mumbai, 400614, India
10Sir PP Institute of Science, Bhavnagar
11Rural College of Pharmacy, D.S Road, Bevanahalli, Banglore

Received : -     Accepted : -     Published : 21-12-2009
Volume : 1     Issue : 2       Pages : 25 - 43
Genetics 1.2 (2009):25-43
DOI : http://dx.doi.org/10.9735/0975-2862.1.2.25-43

Keywords : Biomarkers, Drug development, Drug resistance, Gene therapy, Oncogenomics
Conflict of Interest : None declared

Cite - MLA : Gupta G., et al "Oncogenomics: Clinical pathogenesis approach." International Journal of Genetics 1.2 (2009):25-43. http://dx.doi.org/10.9735/0975-2862.1.2.25-43

Cite - APA : Gupta G., Gupta N., Trivedi S., Patil P., Gupta M., Jhadav A., Vamsi K.K., Khairnar Y., Boraste A., Mujapara A.K., Joshi B. (2009). Oncogenomics: Clinical pathogenesis approach. International Journal of Genetics, 1 (2), 25-43. http://dx.doi.org/10.9735/0975-2862.1.2.25-43

Cite - Chicago : Gupta G., Gupta N., Trivedi S., Patil P., Gupta M., Jhadav A., Vamsi K.K., Khairnar Y., Boraste A., Mujapara A.K., and Joshi B. "Oncogenomics: Clinical pathogenesis approach." International Journal of Genetics 1, no. 2 (2009):25-43. http://dx.doi.org/10.9735/0975-2862.1.2.25-43

Copyright : © 2009, Gupta G., et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Oncogenomics is new research sub-field of genomics, which applies high throughput technologies to characterize genes associated with cancer and synonymous with cancer genomics. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. Oncoproteomics is the term used to describe the application of proteomic technologies in oncology and parallels the related field of oncogenomics. It is now contributing to the development of personalized management of cancer. Genomics has generated a wealth of data that is now being used to identify additional molecular alterations associated with cancer development. Mapping these alterations in the cancer genome is a critical first step in dissecting oncological pathways.

References

[1] Strausberg R.L., et al. (2004) Nature, 429(6990): p. 469-474.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[2] Peeper D. and Berns A. (2006) Cell, 125(7): p. 1230-1233  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[3] Blume-Jensen, P. and T. Hunter (2001) Nature, 411(6835): p. 355-365.26  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[4] Bardelli A., et al., (2003) Science, 300(5621): p. 949-949.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[5] Samuels Y., et al., (2004) Science, 304(5670): p. 554-554  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[6] Ellen G.Feigal, Nicholas C.Dracopoli, and Jeffrey M.Trent (2005) Cancer Res 65 (19): 8587-90  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[7] Minjung Kim, Joseph D.Gans, Cristina Nogueira, Audrey Wang, Ji-HyePaik, BinFeng, Cameron Brennan, William C.Hahn, Carlos Cordon-Cardo, Stephan N.Wagner, Thomas J. Flotte, Lyn M. Duncan, Scott R. Granter and Lynda Chin (2006) Cell 125,1269– 1281  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[8] Borbone E., Berlingieri M.T., De Bellis F., Nebbioso A., Chiappetta G., Mai A., Altucci L., Fusco A. (2009) Oncogene  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[9] Ishikawa K., Tsujimoto G. (2001) Nippon Yakurigaku Zasshi. 118(3):170-6  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[10] Kalliopi Alpantakia, Eleftherios Tsiridisa, Hans-Christoph Papeb and Peter V. Giannoudisa (2007) Injury 38 (3), 263-271.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[11] Karmen Stankov (2006) Arch Oncol 13(2):69-75.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[12] Hyun Goo Woo, Eun Sung Park, Ju-Seog Lee, Yun-Han Lee, Tsuyoshi Ishikawa, Yoon Jun Kim and Snorri S. Thorgeirsson (2009) Cancer Res 69(9):4059–66  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[13] Ivo P. Touw and Stefan J. Erkeland (2007) Molecular Therapy 13–19.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[14] Achatz M.I., Hainaut P., Ashton-Prolla P. (2009) Lancet Oncol. 10(9):920-5  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[15] Murat Cokakli, Esra Erdal, Deniz Nart, Funda Yilmaz, Ozgul Sagol, Murat Kilic, Sedat Karademir and Nese Atabey(2009) BMC Cancer 9:65  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[16] Yamamoto H., Komekado H., Kikuchi A. (2006) Dev Cell 11(2):213-223.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[17] Dittmann K., Mayer C., Kehlbach R., Rodeman H.P. (2008) Mol Cancer 12(7):69  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[18] Lu X., Kambe F., Cao X., Yamauchi M., Seo H. (2008) Exp Cell Res. 314(2):342-351.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[19] Zador E. (2008) Biochem Biophys Res Commun. 375(2):265-70  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[20] Lin J.E., Li P., Pitari G.M., Schulz S., Waldman S.A. (2009) Future Oncol. 5(4):509-22  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[21] Stratford A.L., Habibi G., Astanehe A., Jiang H., Hu K., Park E., Shadeo A., Buys T.P., Lam W., Pugh T., Marra M., Nielsen T.O., Klinge U., Mertens P.R., Aparicio S., Dunn S.E. (2007) Breast Cancer Res. 9(5):R61.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[22] Shrivastav A., Selvakumar P., Bajaj G., Lu Y., Dimmock J.R., Sharma R.K. (2005) Cell Biochem Biophys. 2005; 43(1):189-202  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[23] Munshi N.C. (2008) Hematology Am Soc Hematol Educ Program. 298-305.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[24] Qasim W., Gaspar H.B., Thrasher A.J. (2009) Gene Ther  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[25] Fujii S. (2009) Nihon Rinsho Meneki Gakkai Kaishi. 32(4):231-41  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[26] Echchgadda I., Kota S., Dela Cruz I., Sabbah A., Chang T., Harnack R., Mgbemena V., Chatterjee B., Bose S. (2009) Cancer Gene Ther.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[27] Yonemitsu Y., Ueda Y., Kinoh H., Hasegawa M. (2008) Front Biosci. 13:4953-9.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[28] Edward J. Shillitoe (2009) Head Neck Oncol. 1: 7.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[29] Miwa A. (2007) Gan to Kagaku Ryoho. 34(13):2200-16  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[30] Gomase V.S., Tagore S., Kale K.V., Bhiwgade D.A. (2008) Oncogenomics Curr Drug Metab. 9(3):199- 206.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[31] Arena S., Isella C., Martini M., de Marco A. and Medico E., Bardelli A. (2007) Cancer Res. 67(18):8468-76.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[32] Touw I.P., Erkeland S.J. (2007) vMol Ther. 15(1):13-9  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[33] Di Nicolantonio F., Bardelli A. (2006) Curr Opin Oncol. 18(1):69-76  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[34] Bilke S., Chen Q.R., Whiteford C.C., Khan J. (2005) Bioinformatics. 21(7):1138-45.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[35] Glinsky G.V. (2008) J Clin Oncol. 26(17):2846-53  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[36] De Groot J.F., Gilbert M.R. (2007) Curr Opin Neurol. 20(6):712-8  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[37] Law J.H., Habibi G., Hu K., Masoudi H., Wang M.Y., Stratford A.L., Park E., Gee J.M., Finlay P., Jones H.E., Nicholson R.I., Carboni J., Gottardis M., Pollak M., Dunn S.E. (2008) Cancer Res. 68(24):10238-46.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[38] Gerrit Los, Fei Yang, Goli Samimi, Gerald Manorek, Ivelina M. Guerorguieva, Stephan Howell, Nielka van Erp, and James K. Breaux (2002) Cytometry 47:66–71  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[39] Weiguang Wang, Sharon Marsh, James Cassidy, and Howard L. McLeod (2001) Cancer Research 61, 5505–5510.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[40] Martin Monte, Marta Simonatto, Leticia Y.Peche, Debora R.Bublik, Stefania Gobessi, Marco A.Pierotti, Monica Rodolfo, and Claudio Schneider (2005) PNAS 103(30), 11160-11165  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[41] Kurtis E.Bachman, Jason Sager, Ian Cheong, Marco Catto, Alberto Bardelli, Ben Ho Park, Bert Vogelstein, Angelo Carotti, Kenneth W.Kinzler, and Christoph Lengauer (2005) Mol Cancer Ther. 4(6):1026–30.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[42] Herrmann J.L., Rastelli L., Burgess C.E., Fernandez E.E., Rothberg B.E., Rothberg J.M., Shimkets R.A. (2001) Cancer J. 7(1):40-51.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[43] Ahmad Z., Khurshid A., Qureshi A., Idress R., Asghar N., Kayani N. (2009) Indian J Pathol Microbiol. 52(4):477-81  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[44] Feletti A., Marton E., Rossi S., Canal F., Longatti P., Billeci D. (2009) J Neurooncol.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[45] Pai M.R., Mathai A.M., Kumar S., Prabhu S. (2009) Indian J Pathol Microbiol. 52(4):537-9  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[46] Rodel R.M., Matthias C., Blomeyer B.D., Wolff H.A., Jung K., Christiansen H (2009) Ann Otol Rhinol Laryngol. 118(9):662-9.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[47] Arpaci F., Safali M., Ozet A., Ural A.U., Cetin T., Ozturk M., Ataergin S., Kuzhan O., Komurcu S., Ozturk B., Acikel C. (2009) J Clin Apher  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[48] Albinger-Hegyi A., Stoeckli S.J., Schmid S., Storz M., Iotzova G., Probst-Hensch N.M., Rehrauer H., Tinguely M., Moch H., Hegyi I. (2009) Int J Cancer  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[49] Brautigam E., Track C., Seewald D.H., Feichtinger J., Spiegl K., Hammer J. (2009) Strahlenther Onkol. 185(10):663-8  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[50] Lockwood W. W., Chari R., Coe B.P., Girard L., MacAulay C., Lam S., Gazdar A. F., Minna J.D. and Lam W.L. (2008) Oncogene 4615–4624  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[51] James A. L. Fenton, Guy Pratt., Andy C. Rawstron, Kathryn Sibley, Dominic Rothwell, Zoe Yates, Ann Dring, Steve J. Richards, A. John Ashcroft, Faith E. Davies, Roger G. Owen, J Anthony Child and Gareth J Morgan (2003) Oncogene 1103–1113  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[52] Valeria R. Fantin and Victoria M. Richon (2007) Clinical Cancer Research 13, 7237.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[53] Tai Young Kim., Hyun-Soon Jong., Sang- Hyun Song., Alexandre Dimtchev., Sook-Jung Jeong., Jung Weon Lee., Tae-You Kim., Noe Kyeong Kim., Mira Jung and Yung-Jue Bang (2003) Oncogene 3943– 3951.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[54] Douglas Grossman. and Dario C. Altieri (2001) Cancer and Metastasis 20:3-11  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[55] Tito Fojo., Nick Farrell., Waldo Ortuzar., Hideyuki Tanimura., John Weinstein., Timothy G., Myers (2005) Critical Reviews in Oncology/Hematology, 53 (1), 25-34  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[56] Miller T. P., Chase E. M., Dorr R., Dalton W. S., Lam K .S., Salmon S. E. (1998) Anticancer drugs, 9(2):135-40..  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[57] Dalton W.S, Grogan T.M, Meltzer P.S, Scheper R.J., Durie B.G., Taylor C.W., Miller T.P. and Salmon S.E. (1989) Journal of Clinical Oncology, 7, 415- 424  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[58] Dalton W.S, Grogan T.M, Meltzer P.S, Scheper R.J., Durie B.G., Taylor C.W., Miller T.P. and Salmon S.E. (1989) Journal of Clinical Oncology, 7, 415- 424  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[59] Cole S.P., Bhardwaj G., Gerlach J.H., Mackie J.E., Grant C.E., Almquist K.C., Stewart A.J., Kurz E.U., Duncan A.M. and Deeley R.G. ( 1992) Science, 258 (5088), 1650-1654  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[60] Jason S. Damiano, Anne E. Cress, Lori A. Hazlehurst, Alexander A. Shtil, and William S. Dalton (1999) Blood, 93(5), 1658-1667  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[61] Stratford A.L., Fry C.J., Desilets C., Davies A.H., Cho Y.Y., Li Y., Dong Z., Berquin I.M., Roux P.P., and Dunn SE (2008) Breast Cancer Res. 10(6):R99  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[62] Habibi G., Leung S., Law J.H., Gelmon K., Masoudi H., Turbin D., Pollak M., Nielsen T.O., Huntsman D., Dunn S.E. (2008) Breast Cancer Res. 10(5):R86.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[63] Hideshima T., Mitsiades C., Tonon G., Richardson P.G., Anderson K.C. (2007) Nat Rev Cancer. 7(8):585-98  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[64] To K., Zhao Y., Jiang H., Hu K., Wang M., Wu J., Lee C., Yokom D.W., Stratford A.L., Klinge U., Mertens P.R., Chen C.S., Bally M., Yapp D., Dunn S.E. (2007) Mol Pharmacol. 72(3):641-52  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[65] Rhodes D.R., Yu J., Shanker K., Deshpande N., Varambally R., Ghosh D., Barrette T., Pandey A., Chinnaiyan A.M. (2004) Neoplasia. 6(1):1-6  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[66] Sumathi Ramachandran., Pengbo Liu., Andrew N Young., Qiqin Yin-Goen., So Dug Lim., Noelani Laycock, Mahul B Amin., Jeffrey K. Carney, Fray F. Marshall, John A. Petros and Carlos S. Moreno (2005) Oncogene 188–198  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[67] Rosell., Rafael M.D., Monzo., Mariano M.D, O'Brate., Aurora Ph.D, Taron., Miquel Ph.D (2002) Current Opinion in Oncology, 14 (2), 171-179.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[68] Medico E TRANSFOG Consortium (2008) Tumori. 94(2):172-8.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[69] Sin H.S., Huh J.W., Kim D.S., Kang D.W., Min D.S., Kim T.H., Ha H.S., Kim H.H., Lee S.Y., Kim H.S. (2006) Arch Virol. 151(10):1985-94  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[70] Arkadiusz Welman., Jane Barraclough and Caroline Dive. (2007) Translational Oncogenomics 17–33  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[71] Razvi M.H., Peng D., Dar A.A., Powell S.M., Frierson H.F. Jr, Moskaluk C.A, Washington K., El-Rifai W. (2007) Genes Chromosomes Cancer. 46(10):914-28.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[72] Wu J., Lee C., Yokom D., Jiang H., Cheang M.C., Yorida E., Turbin D., Berquin I.M., Mertens PR, Iftner T., Gilks C.B., Dunn S.E. (2006) Cancer Res. 66(9):4872-9  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[73] Iervolino A., Iuliano R., Trapasso F., Viglietto G., Melillo R.M., Carlomagno F., Santoro M.,Fusco A (2006) Cancer Res. 66(12):6280-7  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[74] Furney S.J., Calvo B., Larranaga P., Lozano J.A., Lopez-Bigas N. (2008) Nucleic Acids Res. 36(18):e115  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[75] Furge K.A., Tan M.H., Dykema K., Kort E., Stadler W., Yao X., Zhou M., Teh B.T. (2007) Oncogene. 26(9):1346-50  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[76] Su W.H., Chao C.C., Yeh S.H., Chen D.S., Chen P.J., Jou Y.S. (2007) Nucleic Acids Res. 35(Database issue):D727- 31.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[77] Jayandharan G.R., Zhong L., Sack B.K., Rivers A.E., Li M., Li B., Herzog R., Srivastava A. (2009) Hum Gene Ther  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[78] Smith K.A., Meisenburg B.L., Tam V.L., Pagarigan R.R., Wong R., Joea D.K., Lantzy L., Carrillo MA., Gross T.M., Malyankar U.M., Chiang C.S., Da Silva D.M., Kundig T.M., Kast W.M., Qiu Z., Bot A. (2009) Clin Cancer Res. 15(19):6167-76  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[79] Fortin C.F., McDonald P.P., Fulop T., Lesur O. (2009) Shock. Colunga A.G., Laing J.M., Aurelian L. (2009) Gene Ther  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[80] Luther D.J., Ohanyan V., Shamhart P.E., Hodnichak C.M., Sisakian H., Booth T.D., Meszaros JG., Bishayee A. (2009) Invest New Drugs.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[81] Wang H.D., Lu D.X., Qi R.B. (2009) Pathophysiology. 16(4):291-6.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[82] Miyazawa M., Yasuda M., Fujita M., Kajiwara H., Hirabayashi K., Takekoshi S., Hirasawa T., Murakami M., Ogane N., Kiguchi K., Ishiwata I., Mikami M., Osamura R.Y. (2009) Pathol Int. 59(1):19-27  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[83] Jain K.K. (2004) Expert Rev Proteomics. 1(1):49-55  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[84] DaRue A Prieto., Xiaoying Ye and Timothy D Veenstra. (2005) Expert Review of Proteomics, 2 (4), 603-614  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[85] Andrew M. Smith., Shivang Dave., Shuming Nie., Lawrence True and Xiaohu Gao. (2006) Expert Review of Molecular Diagnostics 6 (2), 231-244  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[86] Brice P., Sanderson S. (2006) Pharmaceutical Journal 277; 113-4  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[87] Golshan M., Miron A., Nixon A.J., Garber J.E., Cash E.P., iglehart J.D et.al (2006) American Journal of Surgery 192; 58-62  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[88] Schlich-Bakker K.J., ten Kroode H.F.J., Ausems M. (2006) Patients Eduation and Counseling 62(1); 13-20  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[89] Jain K.K. (2004) Expert Rev Proteomics. 1(1):49-55.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[90] Edison T. Liu. (2005) Briefings in Functional Genomics and Proteomics 3(4):303- 321  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[91] Niesner U., Halin C., Lozzi L., Gunthert M., Neri P., Wunderli-Allenspach H., Zardi L., Neri D. (2002) Bioconjug Chem. 13(4):729-36  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[92] Fleming A.B., Saltzman W.M. (2002) Clin Pharmacokinet. 41(6):403-19.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[93] Maeda H. (1989) Gan To Kagaku Ryoho. 16(10):3323-31.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[94] Ohtsuka N., Konno T., Miyauchi Y., Maeda H. (1987) Cancer. 59(9):1560-5  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[95] Maeda H., Konno T., Iwai K., Maki S., Tashiro S. (1984) Gan To Kagaku Ryoho. 11(4):814-26.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[96] Krishnaiah Y.S., Satyanarayana V., Kumar B.D., Karthikeyan R.S. (2002) J Drug Targ. 10(3):247-54  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[97] Keler T., He L., Graziano R.F. (2005) Curr Opin Mol Ther. 7(2):157-63.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[98] Mocellin S., Lise M., Nitti D. (2005) Trends Mol Med. 11(7):327-35  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[99] Argnani R., Lufino M., Manservigi M., Manservigi R. (2005) Gene Ther. 12 Suppl 1:S170-7  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[100] Judge A., McClintock K., Phelps JR., Maclachlan I. (2006) Mol Ther. 13(2):328-37  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[101] Saito R., Kumabe T., Tominaga T. (2006) No Shinkei Geka. 34(11):1157-65.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[102] Liakatos A., Kunz H. (2007) Curr Opin Mol Ther. 9(1):35-44.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[103] McDevitt M.R., Chattopadhyay D., Kappel B.J., Jaggi J.S., Schiffman S.R., Antczak C., Njardarson J.T., Brentjens R., Scheinberg D.A. (2007) J Nucl Med. 48(7):1180-9.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[104] Hellstrom K.E., Hellstrom I. (2007) J Cell Biochem. 102(2):291-300  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[105] Chourasia M.K., Jain S.K. (2003) J Pharm Pharm Sci. 6(1):33-66.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[106] Overwijk W.W., Theoret M.R., Restifo N.P. (2000) Cancer J Sci Am. 6 Suppl 1:S76- 80.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[107] Asada H., Kishida T., Hirai H., Satoh E., Ohashi S., Takeuchi M., Kubo T., Kita M., Iwakura Y., Imanishi J., Mazda O. (2002) Mol Ther. 5(5 Pt 1):609-16  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[108] Lotze M.T., Shurin M., Esche C., Tahara H., Storkus W., Kirkwood J.M., Whiteside T.L., Elder EM., Okada H., Robbins P. (2000) Cancer J Sci Am. 6 Suppl 1:S61- 6.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[109] Prakash S., Jones M.L. (2005) J Biomed Biotechnol. 2005(1):44-56.  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[110] Prakash S., Martoni C. (2006) Appl Biochem Biotechnol. 128(1):1-22  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[111] Cho J.A., Yeo D.J., Son H.Y., Kim H.W., Jung D.S., Ko J.K., Koh J.S., Kim Y.N., Kim C.W. (2005) Int J Cancer. 114(4):613-22  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[112] Hsu D.H., Paz P., Villaflor G., Rivas A., Mehta-Damani A., Angevin E., Zitvogel L., Le Pecq J.B. (2003) J Immunother. 26(5):440-50  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[113] Li X., Zhang Z., Beiter T., Schluesener H.J. (2005) Arch Immunol Ther Exp (Warsz). 53(4):329- 35  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[114] Houot R., Levy R. (2009) Blood Rev. 23(3):137-42  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus  

[115] Cesco-Gaspere M., Zentilin L., Giacca M., Burrone O.R. (2008) Scand J Immunol. 68(1):58-66  
» CrossRef   » Google Scholar   » PubMed   » DOAJ   » CAS   » Scopus