Synthesis and antibacterial studies of some new amides of 5- sulphosalicylic acid

Anjali Mishra¹, Manoj Kumar², Ashok Mishra³, Arvind Kumar⁴, Ravi Kant⁵, Thakur R.S.^6
1Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
²Department of Applied Chemistry, Vidya Bhawan Engineering College, Kanpur
³Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur
⁴Department of Chemistry, K.K. College, Etawah
⁵Department of Medicinal Chemistry, Mahatma Gandhi Institute of Pharmacy, Lucknow
⁶Research Laboratory, Department of Chemistry, D.B.S.P.G. College, Kanpur

Received : -     Accepted : -     Published : 15-06-2010
Volume : 2     Issue : 1       Pages : 28 - 31
Int J Chem Res 2.1 (2010):28-31
DOI : http://dx.doi.org/10.9735/0975-3699.2.1.28-31

Keywords : 5-Sulphosalicylic acid, amines, antibacterial activity
Conflict of Interest : None declared
Acknowledgements/Funding : The authors are highly thankful to the Director RSIC, CDRI Lucknow for spectral and elemental analysis. The authors are also thankful to Principal, D.B.S. P.G. College, Kanpur for providing necessary laboratory facility

Some new amides of 5-Sulphosalicylic acid were synthesized by the reaction of suitable amines with 5-sulphosalicylic acid in 2:1 ratio. The compounds are novel and first time screened for their biological evaluation along with general characterization with the help of elemental analysis, IR spectral analysis. These compounds showed higher to moderate biological activity against different pathogenic microbial strains.

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