Synthesis of some new Acid hydrazones and their activity against Mycobacterium

Srivsatava Ritu¹*, Pandeya S.N.², Singh A.K.³, Anantham Sam^4
1Harish Chandra P.G. College, Varanasi 221001, India
²Saroj Institute of Technology & Management, Ahimamau, Lucknow-226001, India
³Harish Chandra P.G. College, Varanasi 221001, India
⁴TAAFF 2000, Ninth Avenue south, P.O.Box55305, Birmingham Alabama U.S.A
* Corresponding Author : sriritu11@gmail.com

Received : -     Accepted : -     Published : 15-06-2010
Volume : 2     Issue : 1       Pages : 18 - 19
Int J Chem Res 2.1 (2010):18-19
DOI : http://dx.doi.org/10.9735/0975-3699.2.1.18-19

Keywords : Aryl hydrazones, antimicrobial activity
Conflict of Interest : None declared
Acknowledgements/Funding : The authors are highly thankful to the TAAF Birmingham U.S.A. for antimicrobial activity against the bacterial strain

Twelve aryl acetic acid hydrazones were synthesized and tested first time for their antimicrobial activity. The structures of all these compounds were confirmed with the help of IR, 1HNMR, Mass spectra along with elemental analysis. Some of the target compounds show moderate activity against H37 RV strain of Mycobacterium tuberculosis at a concentration of 10μM.

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