The adverse ecological conditions caused to the commercial Seabreams: Diplodus sargus sargus L., Rhabdosargus sarba F., and Crenidenscrenidens F., fish was observed due to the increase in wastewater pollution. Using DESCAR-3.2 software program, trace metals trajectories from the drain outfalls was modeledbesides, the laboratory assessment of static toxicity and bioaccumulation tests. The wastewater discharged from seven drain outfalls (SI-SVII) showed high trace metals sequence (Zn>Fe>Cu>Pb>Cr>As>Hg) during winter than in the summer seasons. Toxicity tests showed high trace metals sensitivity in the sequence of C. crenidens>D. sargus>R. sarba. Bioaccumulation factor (BAF) >1 in these fish exposed for 30d indicated significant trace metals accumulation from wastewater. Fish indicating BAF <1 suggested the trace metals in their body parts was due to the adsorption process or through victuals. This novel multidimensional study not only labelled the sampled fish species as bio-indicator and bio-accumulator to wastewater pollution but also, validated the specific seasonal orientation and dispersion of wastewater into the marine environment unlike earlier findings in the region.