Since the Ministry of Health implemented deworming programs in schools in 2012, there have been limited studies on the prevalence of helminth-related infections in Côte d’Ivoire, particularly in Man. Hence, determining the magnitude of intestinal helminth infections and identifying factors that can increase the risk of infection are important for establishing the effectiveness of government programs and monitoring the health and disease risk of the population. This cross-sectional study was conducted among 400 children aged 4–15 years in urban areas in Man, western Côte d’Ivoire. Single stool samples were, and analyzed using the Kato-Katz, simplified Ritchie, and Baermann techniques. Overall,23.3% (95% CI = 19.3–27.6) of children were found to be infected with one or more species of intestinal helminths, including Ascaris lumbricoides (32.3%), hookworms (33.3%), Schistoso mamansoni (18.3%),Trichuris trichiura (10.8%), Strongyloides stercoralis (4.3%), and Taenia sp (3.23%). Biparasitism was observed among 2.2% of the pupils. Deworming during the last 6 months was associated with a decline in the incidence of parasitism (p=0.02).Age and drinking water supply (p=0.03) were linked to cases of intestinal parasitism. The use of rivers was associated with the occurrence of S.mansoni infection (p=0.002). However, gender and fecal matter disposal mode were not significantly associated with parasitism (p>0.05). Overall, these results demonstrate that the prevalence of intestinal helminthiasis in Man is high, posing a substantial threat to the health of children. This situation could be improved by mass treatments and appropriate hygiene measures.