Background and Aim: Dengue is the most rapidly spreading mosquito borne viral disease of mankind, with a 30 folds increase in global incidence over the last five decades. It is a significant public health issue in the tropical and subtropical parts of the world. The present study was conducted with objective to study prevalence of dengue in during the year 2018 in Kutch region, Gujarat, India. Methods: This study was carried out from January 2018 to December 2018 at Department of Microbiology, Gujarat Adani Institute of Medical Sciences, G.K. General Hospital, Bhuj. The patients having suspected dengue fever was based on standard criteria like presentation of febrile illness of 2-7 days duration were included in this study. A total of 857 blood samples were collected during study period and serologically tested for dengue NS1 antigen and IgM antibody by capture ELISA testing method. Results: Total 857 blood samples from across the Kutch region were tested by ELISA for NS1 antigen and/or IgM antibody as per the protocols and personal, demographic and clinical details of each patient was recorded. Out of 857 cases 113 tested positive for dengue. Among all positive cases 74(12%) were tested positive for NS1 antigen which helped in early diagnosis of dengue. Rise of dengue cases started after the month of October and falls down by the end of December. Analysis of this data revealed that age group 00-10 years had maximum dengue cases. Male cases 68(60%) were more than females 45(40%). Dengue cases were high in urban area. Conclusion: According to the current study, dengue primarily impacted urban populations, men, and children. It was noted that the occurrence was perennial and increased seasonally during the monsoon and after the monsoon. The community's prevalence of dengue will decrease with the effective application of vector control measures through efforts to reduce vector breeding sources and with the adoption of individual preventive measures against mosquito bites