Hereditary spherocytosis (HS) is a rare type of hemolytic anemia in southeast-Asian population whereas it is common among western countries like north Europe. Hereditary Spherocytosis (HS) is most common red cell membrane disorder with varying degrees of clinical severity, membrane protein defect and modes of inheritance. In majority of cases transmission is autosomal dominant .Severity of the disease is classified as mild, moderate and severe forms. 3-5% of the patients have severe disease and often complicated by cholelithiasis. Though severe form is an indication for splenectomy presently evidence favouring the conservative approach to splenectomy. There are only few case report series concerning the pregnancy complicated by HS. Though hemolytic crisis was managed conservatively in some cases, outcome of pregnancy was more favorable after splenectomy than before. We report a case of HS with post splenectomy complicated pregnancy with good maternal and fetal outcome.

Introduction: CNS (central nervous system) tumors are the most common solid tumors in children. Tumors of the central nervous system can be divided into primary intracranial tumours that arise from parenchyma of brain, pituitary gland, covering of brain & secondary intracranial tumours which represent local extension from regional tumours or metastasis from primary malignancy in the body. The most common location of the brain tumours in childhood is below the tentorium within the posterior cranial fossa. Materials and methods: Fifty-eight surgical specimen of central nervous system of children (0 to 14 year of age group) received from August 2014 to July 2016, in the Tertiary care centre, Ahmedabad were studied with keeping the following features in mind: Age, Sex and site of tumours. Results: Fifty-eight cases of Central Nervous System Tumours between the age of 0 to 14 years over a period of 2 years at civil hospital, Ahmedabad were studied. Incidence were more common in male (60.34%) than female (39.66%). 89.65% of tumors were intracranial and 10.35% were intraspinal tumours. Commonly encountered tumour in descending order of frequency were Medulloblastoma (27.58%), astrocytoma (24.13%), Ependymoma (20.68%). All medulloblastomas arose infratentorial, schwannomas arose intraspinal and meningiomas in cranial cavity are supratentorial. Conclusion: CNS Tumors constitute a large proportion of cancers in childhood. They differ from adult CNS tumors both histologically and location wise. Site of the tumor is significant as it can lead to fatal consequences.