The present review article deals the advancement in bioorganometallic and Metalopharmaceuticals applications and perspectives of group-15 elements in recent past. It is well known that organometallics of group-15 elements shows vast potentiality in biomedical research in past few years and used in the treatment of various chronic and acute diseases. The authors tried to compile literature regarding this area of research in the manuscript up to date along with brief out lines of medicinal importance of metals.