RAPID DIAGNOSIS OF INVASIVE FUNGAL INFECTION DURING COVID PANDEMIC ERA-ROLE OF POTASSIUM HYDROXIDE PREPARATION

M.C. PATANKAR1, S.T. SONI2*, H.S. SHAH3, V.R. PATEL4, S.C. UPADHYAY5, P.M. PATEL6, P.P. ROHIT7
1Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
2Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
3Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
4Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
5Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
6Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
7Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
* Corresponding Author : drsumeetasoni@gmail.com

Received : 01-09-2021     Accepted : 26-09-2021     Published : 30-09-2021
Volume : 13     Issue : 4       Pages : 1963 - 1965
Int J Microbiol Res 13.4 (2021):1963-1965

Keywords : Mucormycosis, Covid 19 infection, KOH preparation
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology, B. J. Medical College, Gujarat University, Ahmedabad, Gujarat, 380016, India
Author Contribution : All authors equally contributed

Cite - MLA : PATANKAR, M.C., et al "RAPID DIAGNOSIS OF INVASIVE FUNGAL INFECTION DURING COVID PANDEMIC ERA-ROLE OF POTASSIUM HYDROXIDE PREPARATION." International Journal of Microbiology Research 13.4 (2021):1963-1965.

Cite - APA : PATANKAR, M.C., SONI, S.T., SHAH, H.S., PATEL, V.R., UPADHYAY, S.C., PATEL, P.M., ROHIT, P.P. (2021). RAPID DIAGNOSIS OF INVASIVE FUNGAL INFECTION DURING COVID PANDEMIC ERA-ROLE OF POTASSIUM HYDROXIDE PREPARATION. International Journal of Microbiology Research, 13 (4), 1963-1965.

Cite - Chicago : PATANKAR, M.C., S.T. SONI, H.S. SHAH, V.R. PATEL, S.C. UPADHYAY, P.M. PATEL, and P.P. ROHIT. "RAPID DIAGNOSIS OF INVASIVE FUNGAL INFECTION DURING COVID PANDEMIC ERA-ROLE OF POTASSIUM HYDROXIDE PREPARATION." International Journal of Microbiology Research 13, no. 4 (2021):1963-1965.

Copyright : © 2021, M.C. PATANKAR, et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Introduction: Mucormycosis is a life-threatening angioinvasive infection caused by fungi of the order Mucorales and class of Mucormycetes. It is common in covid and diabeticketoacidosis patients. Main sources of mucormycosis in hospital settings are mechanical supply of oxygen and environmental contamination. It is rapid grower, angioinvasive and destructive for human body, so rapid diagnosis and treatment is necessary. Methods: This study was conducted for suspected samples received at microbiology laboratory of civil hospital during May and June 2021. Samples are treated with KOH preparations and findings were noted down. All findings are compared with biopsy findings and radiological findings and results are noted down. Result: A total of 1070 samples were screened from which 204 samples were found positive for fungal elements resembling mucormycosis showing that it was more prevalent among all fungal infections in that time period. Highest number of positive samples are tissue samples. More number of samples are of male patients than female patients. Age group of 31-60 years are more affected from this disease. More number of positive patients are diabetic considering it as a risk factor for this disease. Conclusion: After pandemic wave of covid 19 there was increasing prevalence of mucormycosis patients showing some relation of it to covid 19 infection. Mucormycosis was most prevalent fungal infection among all fungal infections in that post covid 19 pandemic wave. As it was fatal to human beings it was necessary to detect this fungal infection by any rapid proven method and KOH preparation method was proven as best method for rapid detection

References

1. Bala K., Chander J., Handa U., Punia R.S. and Attri A.K. (2015) Medical Mycology, 53, 248–257.
2. Centre for Disease Control and Prevention (2021)
3. Gautam M., Bhatia S. (2020) Indian J Paediatr Dermatol., 21, 343-6.
4. Fisher F.W. and Cook N.B. (1998) Fundamentals of diagnostic mycology, W.B. Saunders, Philadelphia.
5. Mycology laboratory, Tertiary care teaching hospital, B. J. Medical College, Ahmedabad, Gujarat, 380016, India
6. Skiada A., Pavleas I., Drogari-Apiranthitou M. (2020) Journal of Fungi, 6(4), 265.
7. Prakash H., Ghosh A.K., Rudramurthy S.M., Singh P., Xess I., Savio J., et al., (2019) Medical mycology 57 (4), 395-402.
8. Jagdish Chander (2018) Textbook of Medical Mycology, ISBN-9789386261830, Jaypee Brothers Medical Publishers, India.