PREVALENCE OF BACTERIAL INFECTIONS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PATIENTS ADMITTED IN INTENSIVE CARE UNIT

N. AKSHAYA1, K. SHARANYA2, K. LAKSHMI3*
1Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, 600044, India
2Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, 600044, India
3Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, 600044, India
* Corresponding Author : laksh45@gmail.com

Received : 01-10-2020     Accepted : 21-10-2020     Published : 30-10-2020
Volume : 12     Issue : 10       Pages : 1909 - 1912
Int J Microbiol Res 12.10 (2020):1909-1912

Keywords : Bacterial organisms, Antibiotic susceptibility pattern, Intensive care unit
Academic Editor : Dr Jitendra Malviya, Ranabijuli S
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, 600044, India
Author Contribution : All authors equally contributed

Cite - MLA : AKSHAYA, N., et al "PREVALENCE OF BACTERIAL INFECTIONS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PATIENTS ADMITTED IN INTENSIVE CARE UNIT." International Journal of Microbiology Research 12.10 (2020):1909-1912.

Cite - APA : AKSHAYA, N., SHARANYA, K., LAKSHMI, K. (2020). PREVALENCE OF BACTERIAL INFECTIONS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PATIENTS ADMITTED IN INTENSIVE CARE UNIT. International Journal of Microbiology Research, 12 (10), 1909-1912.

Cite - Chicago : AKSHAYA, N., K. SHARANYA, and K. LAKSHMI. "PREVALENCE OF BACTERIAL INFECTIONS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PATIENTS ADMITTED IN INTENSIVE CARE UNIT." International Journal of Microbiology Research 12, no. 10 (2020):1909-1912.

Copyright : © 2020, N. AKSHAYA, et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Infections in Intensive care unit (ICU) patients remain as a great challenge to the treating health care providers due to their high incidence and mortality rates. Aim: The aim of the present study is to evaluate the prevalence and the antibiotic susceptibility pattern of bacterial infections from patients admitted in ICU. Materials and methods: The study was conducted in a tertiary care hospital, Chennai. Clinical samples were collected from 100 patients admitted in the ICU with clinical symptoms of infection and processed in microbiology laboratory for bacterial culture and sensitivity. The organisms were identified using standard microbiological methods. Results: Out of the 100 samples processed, 61 samples showed bacterial growth. The common infections in ICU were found to be urinary tract infections, septicaemia, respiratory infections followed by soft tissue infections. Escherichia coli, Klebsiella, Staphylococcus aureus, Coagulase negative Staphylococcus (CONS) and Pseudomonas were the commonly isolated organisms. Conclusion: Patients in ICU are reported to be highly susceptible to infections. Drug resistance is found to be higher among the isolates. Strict adherence to Hospital infection control protocol, proper monitoring of the patients and rational use of antibiotics help in prevention of infections to a greater extent

References

1. Inan D., Saba R., Gunseren F., Ongut G., Turhan O., Yalcin A.N., et al. (2005) BMC Infect Dis., 5, 5.
2. Kuhlen R. (2007) 25 Years of Progress and Innovation in Intensive Care Medicine. 1 edition. Berlin: Mwv.
3. Brusselaers N., Vogelaers D., Blot S. (2011) Ann Intensive Care, 1, 47.
4. Barai L., Fatema K., Ashraful Haq J., Omar Faruq M., Areef Ahsan A.S., Golam Morshed M.A. (2010) Ibrahim Med Coll J., 4, 66-9.
5. Gunserena F., Mam?koglua L., Ozturkb S., Yucesoyc M., Biberogluc K., Yulugc N.A. (1999) J Antimicrob Chemother. 43, 373-8.
6. Gupta V., Singla N., Gombar S., Palta S., Chander J. (2018) J Assoc Chest Physicians, 6, 4-11.
7. Hotchkiss R.S., Monneret G., Payen D. (2013) Lancet Infect Dis., 13, 260-8.
8. Conway Morris A., Datta D., Shankar-Hari M., et al. (2018) Intensive Care Med., 44, 627-35.
9. McGowan J.E. (1983) Rev Infect Dis., 5, 1033-48.
10. Marr J.J., Moffet H.L., Kunin C.M. (1988) J Infect Dis.,157, 869-76.
11. Luyt C.E., Bréchot N., Trouillet J.L., et al. (2014) Crit Care, 18, 480.
12. Tran G.M., Ho-Le T.P., Ha D.T., Tran-Nguyen C.H., Nguyen T.S.M., Pham T.T.N., Nguyen T.A., Nguyen D.A., Hoang H.Q., Tran N.V., Nguyen T.V. (2017) BMC Infect Dis., 17(1), 429.
13. Moolchandani K., Sastry A.S., Deepashree R., Sistla S., Harish B.N., Mandal J. (2017) J Clin Diagn Res., 11(2), DC01-DC07.
14. Anand N., Nagendra Nayak I.M., Advaitha M.V., Thaikattil N.J., Kantanavar K.A., Anand S. (2016) Indian J Crit Care Med., 20, 274-79.
15. Patel M.K., Barvaliya M.J., Patel T.K., Tripathi C. (2013) Int J Crit Illn Inj Sci., 3(4), 250-55.
16. Kaushal V Sheth, Tejas K Patel, Saklainhaider S Malek and CB Tripathi. (2012) Trop J Pharm Res, 11 (6), 991
17. Varghese G.K., Mukhopadhyay C., Bairy I., Vandana K.E., Varma M. (2010) J Assoc Physicians India, 58(Suppl), 23-24.
18. Lepape A., Monnet D.L. (2009) Euro Surveill 2009; 14 (45), p ii=19393.
19. Chawla K., Madan A., Chawla R.K., Chawla A.K. (2014) J Nat Accred Board Hosp Healthcare Providers., 1, 44-51.
20. Vincent J.L., Rello J., Marshall J., Silva E., Anzueto A., Martin C.D., et al. (2009) JAMA., 302(21), 2323-29.
21. Nagarjuna D., Mittal G., Dhanda R.S., Gaind R., Yadav M. (2018) Antimicrob Resist Infect Control., 7, 150.
22. Masgala A., Kostaki K., Ioannnidis I. (2015) J Infect Dis Diagn., 1, 101.
23. Jamshidi M., Javadpour S., Eftekhari T.E., Moradi N., Jomehpour F. (2009) Afr J Microbiol Res., 3(10), 590-94.
24. Chawla K., Vishwanath S., Munim F.C. (2013) J Glob Infect Dis., 5(4), 144-48.
25. Mohammadi-mehr M., Feizabadi M.M. (2011) Iran J Microbiol., 3(1), 26-30.
26. Sheth K.V., Patel T.K., Malek S.S., Tripathi C.B. (2012) Tropical Journal of Pharmaceutical Research, 11(6), 991-99.
27. Tuhina Banerjee, Anwita Mishra, Arghya Das, Swati Sharma, Hiranmay Barman and Ghanshyam Yadav (2018) Journal of Pathogens, Vol 2018, Article ID 9129083. 8 pages.
28. Sharma P.R., Barman P. (2010) Indian J Pharmacol., 42, 301-305.
29. Zhanel G.G., DeCorby M., Laing N., Weshnoweski B., Vashisht R., Tailor F. (2008) Antimicrob Agents Chemother., 52, 14301437.
30. Raghunath D. (2008) J. Biosci., 33(4), 593-603.
31. Rijnders M.I.A., Deurenberg R.H., Boumans M.L.L., Hoogkamp-Korstanje J.A.A., Beisser P.S., Stobberingh E.E. (2009) J Antimicrob Chemother., 64, 1029-1034.
32. Patil P.S., Bhalchandra M.H., Rangaiahagari A. and Nagaraju V. (2017) Indian journal of Mednodent and Allied Sciences, 5(1), 9- 14.
33. Abbas A., Nirwan P.S., Srivastava P. (2015) Commun Acquired Infect., 2(1), 13-5.
34. Mantri R.S., Karyakarte A.R., Ambhore N.A. and Kombade S.P. (2014) Int J Curr Microbiol Appl Sci., 3(10), 582-6.
35. Joshi S., Ray P., Manchanda V., Bajaj J., Chitins D.S., et al. (2013) Indian J Med Res.,137, 363-9.