PREVALENCE OF GROUP A STREPTOCOCCUS (GAS) CAUSING SORE THROAT IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL OF WESTERN ODISHA

S. MISHRA1, S. MUKHERJEE2*, S. TIWARI3
1Department of Microbiology, Hitech Medical College, Rourkela, 769004, Odisha, India
2Department of Microbiology, Hitech Medical College, Rourkela, 769004, Odisha, India
3Department of Microbiology, Hitech Medical College, Rourkela, 769004, Odisha, India
* Corresponding Author : shuvankar.mukherjee963@gmail.com

Received : 02-03-2020     Accepted : 27-03-2020     Published : 30-03-2020
Volume : 12     Issue : 3       Pages : 1798 - 1800
Int J Microbiol Res 12.3 (2020):1798-1800

Keywords : Streptococcus, Pharyngitis, Prevalence, Odisha
Academic Editor : Indu V. R., Kumar D Shiva, Abdel Raheem M. A., Dr Ranjana Hawaldar, U. Y. Kandekar
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology, Hitech Medical College, Rourkela, 769004, Odisha, India
Author Contribution : All authors equally contributed

Cite - MLA : MISHRA , S., et al "PREVALENCE OF GROUP A STREPTOCOCCUS (GAS) CAUSING SORE THROAT IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL OF WESTERN ODISHA ." International Journal of Microbiology Research 12.3 (2020):1798-1800.

Cite - APA : MISHRA , S., MUKHERJEE, S., TIWARI , S. (2020). PREVALENCE OF GROUP A STREPTOCOCCUS (GAS) CAUSING SORE THROAT IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL OF WESTERN ODISHA . International Journal of Microbiology Research, 12 (3), 1798-1800.

Cite - Chicago : MISHRA , S., S. MUKHERJEE, and S. TIWARI . "PREVALENCE OF GROUP A STREPTOCOCCUS (GAS) CAUSING SORE THROAT IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL OF WESTERN ODISHA ." International Journal of Microbiology Research 12, no. 3 (2020):1798-1800.

Copyright : © 2020, S. MISHRA, et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Back ground -Group A Streptococcus (GAS) is one of the most common cause of pharyngitis. It may lead to rheumatic heart disease as complication. Prevalence of GAS pharyngitis in India is 4.2-13.7%. A study was conducted to find out prevalence of Group A Streptococcus causing sore throat in patient attending a tertiary care hospital of Western Odisha. Materials & method- Throat swabs of 350 patients presenting with sore throat were collected aseptically and culture was done as per standard protocol. Streptococcus pyogenes was identified with the help of colony morphology, bacitracin disc (0.04U) and group A specific antisera. Blood sample was collected from all culture positive patients and was tested for ASO test. GAS pharyngitis was considered only when patient was positive in both culture and ASO test. Antibiotic sensitivity test was performed as per CLSI guideline. Result-Prevalence of Group A Streptococcus in sore throat patients was 6%. Most of the positive cases were found in rainy season and in young (<30 yrs) patients of female sex. Penicillin and Amoxy clav showed 100% sensitivity against GAS and Erythromycin was 86% sensitive. Levofloxacin showed high resistance rate (43%). Conclusion- Prevalence of GAS in Western Odisha was lower than most of the studies in India. Penicillin and Amoxycillin were still 100% sensitive against GAS.

References

1. Tesfaw G., Kibru G., Mekonnen D., Abdissa A. (2015) Egyptian Journal of Ear, Nose, Throat and Allied Sciences,16(1), 35-40.
2. Mathur N.B. (1991) Indian Pediatrics, 29, 1071-1075.
3. World Health Organization (1980) WHO Technical Report Series, No. 642.
4. Sarkar S., Biswas R., Gaur S.D., Sen P.C., Reddy D.C. (1988) Indian J Public Health, 1988, 32, 190-8.
5. Koshi G., Benjamin V. (1977) Indian J Med Res., 66, 379-88.
6. Gupta R., Prakash K., Kapoor A.K. (1992) Indian Pediatrics, 29, 1491-1494.
7. Uzodimma C.C., Dedeke F.I., Nwadike V., Owolabi O., Arifalo G., Oduwole O. (2017) Nig J Cardiol,14,97-102.
8. Nandi S., Kumar R., Ray P., Vohra H., Ganguly N.K. (2001) Bulletin of the World Health Organization,79, 528-33.
9. The Clinical & Laboratory Standards Institute (CLSI) (2016) CLSI Supplement M100S. 26th ed. Wayne, PA, The Clinical and Laboratory Standards Institute
10. Oliver J., Wadu E.M., Pierse N., Moreland N.J., Williamson D.A., Baker M.G. (2018) PLoS neglected tropical diseases, 12(3), e0006335.
11. Rotta J., Duben J., Jedli?ka F., Havlí?ková H., T?mová B., Br??ková M. (1989) Zentralblatt für Bakteriologie, 271(4), 532-42.
12. Ba-Saddik I.A., Munibari A.A., Alhilali A.M., et al., (2014) Trop Med Int Health,19(4),431-439.
13. Rimoin A.W., Walker C.L.F., Hamza H.S., et al., (2010) Int J Infect Dis,14(12),1048-1053.
14. Mzoughi R., Bouallegue O., Selmi H., Ben Said H., Essoussi A.S., Jeddi M. (2004) La Revue de Santé de la Méditerranée orientale, 10, No 4/5,
15. Bassili A., Barakat S., Sawaf G.E., Zaher S., Zaki A., Saleha E.E. (2002) Journal of Tropical Pediatrics, 48(5), 285-93.
16. Nayiga I., Okello E., Lwabi P., Ndeezi G. (2017) BMC infectious diseases,17(1), 248.
17. WHO Regional Office for South-East Asia, New Delhi (1987) Manual of reference procedures in streptococcal bacteriology.
18. Reed B.D., Huck W., French T. (1990) Archives of Internal Medicine,150(8),1727-32.
19. Van Cauwenberge P.B., Vander Mijnsbrugge A.M. (1991) The Pediatric Infectious Disease Journal,10(10), S39-42.
20. Duben J., Jelinkova J., Jelinek J., Rotta J. (1979) Journal of Hygiene, Epidemiology, Microbiology, and Immunology, 23(2),159-67.
21. Bhardwaj N., Mathur P., Behera B., Mathur K., Kapil A., Misra M.C. (2018) The Indian Journal of Medical Research,147(1), 81.
22. Dhanda V., Chaudhary P., Toor D., Kumar R., Chakraborti A. (2013) J Med Microbiol., 62, 386-93.
23. Brown D.F., Hope R., Livermore D.M., Brick G., Broughton K., George R.C., et al., (2008) J Antimicrob Chemother., 62(Suppl 2), ii75-85.
24. Asmah N., Eberspächer B., Regnath T., Arvand M. (2009) J Med Microbiol, 58, 222-7.