ANTIBIOTIC RESISTANCE PATTERN OF E.COLI ISOLATES FROM URINE: 3 YEAR RETROSPECTIVE STUDY

N. GUPTA¹, N.R. GANDHAM²*, R.N. MISRA³, S.B. MIRZA⁴, K.M. ANGADI⁵, C.R. VYAWAHARE^6
1Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
²Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
³Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
⁴Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
⁵Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
⁶Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
* Corresponding Author : nageswari_rg@rediffmail.com

Received : 26-02-2020     Accepted : 27-03-2020     Published : 30-03-2020
Volume : 12     Issue : 3       Pages : 1781 - 1784
Int J Microbiol Res 12.3 (2020):1781-1784

Keywords : Urinary tract infections, Antibiotic resistance, Surveillance
Academic Editor : Dr Mudit Chandra, Rajpal Diwakar, Dr M.G. Rathod
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, 411018, Pune, India
Author Contribution : All authors equally contributed

Background- Urinary tract infections (UTI) by E.coli are very common in clinical practice. In last few years antimicrobial resistance has increased that can result in treatment failure. Antibiotic sensitivity pattern may vary in different geographical locations. Aim of this study is to determine the pattern of antimicrobial resistance to E.coli among the UTI patients. Retrospective observational study of last three years (Jan 2017- Dec 2019) was done from microbiological record of urine samples. Information of patients with UTI caused by E.coli were recorded with their Antimicrobial resistance pattern. E.coli was 43% from the total positive culture isolates. Antibiotic resistance observed high for Nalidixic acid (88.5%), Cefotaxime (72.1%), Norfloxacin (71%), Ceftazidime (63.7%), Cotrimoxazole (58.4%) Cefoxitin (51.4%) and low resistance for Gentamicin (32.1%), Amikacin (13.4%), Piperacillin-Tazobactam (12.2%), Imipenem(5.9%) and Nitrofurantoin (5.8%). Conclusion- Due to high antimicrobial resistance to most commonly prescribed antibiotics, we recommend that Nitrofurantoin can be used as empirical treatment option in UTI due to low resistance.

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