STUDY OF PREDISPOSING FACTORS AND AETIOLOGIC DIAGNOSIS OF INFECTIOUS KERATITIS

C.R. VYAWAHARE¹, N.R. GANDHAM²*, S.V. JADHAV³, R.N. MISRA^4
1Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, 411018, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
²Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, 411018, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
³Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, 411018, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
⁴Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, 411018, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
* Corresponding Author : nageswari_rg@rediffmail.com

Received : 28-08-2019     Accepted : 26-09-2019     Published : 30-09-2019
Volume : 11     Issue : 9       Pages : 1697 - 1700
Int J Microbiol Res 11.9 (2019):1697-1700

Keywords : Keratitis, Microbial, Mycotic, Bacterial, Trauma
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, 411018, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
Author Contribution : All authors equally contributed

Introduction: Microbial keratitis is a potentially vision-threatening ocular infection that may be caused by bacteria, fungi, viruses or parasites. The etiological and epidemiological features of keratitis depend on host factors, geographical location and the climate. Several risk factors like age, sex, immune status and socio-economic background determine its pathogenesis. Therefore, knowledge of above features plus local organisms and resistance patterns help in rapid identification and appropriate selection of antimicrobial therapy. Aims and objective: To analyse the aetiology and predisposing factors associated with microbial keratitis. Material and methods: Corneal scraping from 100 suspected cases of infectious keratitis were included in the study. They were processed by standard microbiological procedures for isolation and speciation of different microbial agents. Result: Of the 100 patients investigated bacterial growth was found in 26 (26%) patients while fungal growth in 39 (39%) patients. Filamentous fungi isolated predominantly (95%), of which Aspergillus spp (25.6%) was commonest followed by Fusarium spp (17.9%), Penicillium spp (10.2%) etc. C. albicans were found in 2 (5%) patients. Of the positive bacterial culture Staphylococcus aureus (26.9%) were predominant followed by CONS and Pseudomonas aeruginosa (15.3%), E.coli (11.5%) etc. Trauma was commonest predisposing factor. Conclusion: An understanding of the epidemiological features, risk factors, and etiological agents for microbial keratitis in a specific region is important in rapid recognition, timely institution of therapy, optimal management, and prevention of this disease.

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