ISSN : 0975-5276
EISSN : 0975-9174
TANDRA CHADHA1*, SHASHIKANT ADLEKHA2
1Department of Microbiology, Rajshree Institute of Medical Sciences and Research, Bareilly, 243501 India
2Department of Pathology, Rajshree Institute of Medical Sciences and Research, Bareilly, 243501 India
* Corresponding Author : ruc.isha@gmail.com
Received : 14-10-2018 Accepted : 26-10-2018 Published : 30-10-2018
Volume : 10 Issue : 10 Pages : 1378 - 1380
Int J Microbiol Res 10.10 (2018):1378-1380
Keywords : HBV, HCV, HIV, First time Donors, Voluntary Donors, Repeat Donors, Replacement Donors
Conflict of Interest : None declared
Acknowledgements/Funding : Author thankful to Rajshree Institute of Medical Sciences and Research, Bareilly, 243501 India
Author Contribution : All author equally contributed
Background: The World Health Organization recommendation necessitates universal screening of blood donations for the major transfusion-transmissible infections (TTIs):Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human immunodeficiency virus (HIV), and syphilis. Blood-borne agents such as the human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) are among the greatest threats to blood safety for the recipient. This study aimed to determine the seroprevalence of HBV, HCV and HIV infections among first-time blood donors(FD) in a blood bank in tertiary care medical college hospital in Western Uttar Pardesh, Bareilly, India. Methods: This retrospective study was based on the records of all voluntary(VD) and replacement donations(RPD)which were collected from January 2016 to August 2018 in a tertiary care medical college and hospital in Bareilly, Uttar Pradesh, India. Results: Of the total 7908 donations, 2268 (28.6%) were voluntary and 5640 (71.4%) were replacement donation. The first-time donor accounted for 5024 (63.6%), while repeat donors (RD) accounted for remaining 36.4%. The TTIs were more frequently encountered in First Time donors in comparison to Repeat donors. Also, when first time donors were analysed alone, the prevalence of TTIs was more in replacement donors, compared to voluntary donors. Conclusions: The potential risk of TTIS can be truncated to a large extent by increasing in public awareness regarding frequent blood donation and voluntary blood donation, donor screening using stringent criteria, counselling and use of highly sensitive and specific tests.
1. World Health Organization (2008) Universal access to safe blood transfusion. Geneva, WHO, 2008.
2. Rawat A., Diwaker P., Gogoi P., Singh B. (2017) Indian J Med Res., 146,642-5.
3. Wasfi OASSN. (2011) East Mediterr Health J., 17(3),238–42.
4. Saghir S.A.M., Hassan F.M.A., Alsalahi O.S.A., Alhariry A.E.A.A., Baqir H.S. (2012) Trop J Pharm Res., 11(1),132–6.
5. Singh R., Vohra P., Singla P., Chaudhary U. (2013) J Evol Med Dent Sci., 2(26),4816–20.
6. Kafi-abad S.A., Rezvan H., Abolghasemi H., Talebian A. (2009) Transfusion, 49,2214–20.
7. Chaudhary I.A., Samiullah, Khan S.S., Masood R., Sardar M.A., Mallhi A.A. (2007) Pak Med J., 23, 64-7.
8. Mollah A.H., Nahar N., Siddique M.A., Anwar K.S., Hassan T., Azam M.G., et al. (2003) J Health Popul Nutr.,21, 67-71.
9. Blood safety, a strategy for the African region. AFR/RC51/R2. Brazzaville, WHO Regional Office for Africa, 2001.
10. Tapko J.B., Mainuka P., Diarra-Nama A.J. Status of blood safety in the WHO African Region, report of the 2006 survey. Brazzaville, WHO Regional Office for Africa, 2009.
11. Tagny C.T., Owusu-Ofori S., Mbanya D., Deneys V. (2010) Transfus Med.,20,1–10.
12. Madhava V., Burgess C., Drucker E. (2002) Lancet Infect Dis., 2, 293–302.
13. Jacobs B., Mayaud P., Changalucha J., Todd J., Ka-Gina G., Grosskurth H., Berege Z.A. (1997) Sex Transm Dis., 24,121–6.
14. Dokekias A.E., Okandze-Elenga J.P., Kinkouna A.G., Lepfoundzou A.B., Garcia S. (2003) Bull Soc Pathol Exot., 96,279–82.
15. Mohammed and Bekele (2016) BMC Res Notes., 9, 129.