EPIDEMIOLOGY OF ACINETOBACTER SPECIES IN A TERTIARY CARE HOSPITAL WITH SPECIAL REFERENCE TO SEASONAL VARIATION

NEETU GUPTA¹, NAGESWARI GANDHAM²*, SAVITA JADHAV³, RABINDRA NATH MISRA⁴, KALPANA ANGADI⁵, CHANDA VYAWAHARE^6
1Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
²Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
³Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
⁴Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
⁵Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
⁶Department of Microbiology, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr D.Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
* Corresponding Author : nageswari.rg@gmail.com

Received : 18-06-2018     Accepted : 27-06-2018     Published : 30-06-2018
Volume : 10     Issue : 6       Pages : 1283 - 1286
Int J Microbiol Res 10.6 (2018):1283-1286
DOI : http://dx.doi.org/10.9735/0975-5276.10.6.1283-1286

Keywords : Acinetobacter spp, ICUs, Epidemiology, Multidrug resistance
Conflict of Interest : None declared
Acknowledgements/Funding : Authors are thankful to Department of Microbiology Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth, Pimpri, Pune, 411018
Author Contribution : All authors contributed equally

Background: The members of the genus Acinetobacter are persistent nosocomial pathogens. Strains with increased resistance to most β-lactam antibiotics, fluoroquinolones, and aminoglycosides continue to be detected worldwide. They are responsible for various nosocomial infections. This study aimed to find the prevalence, epidemiology, and changing trend of this organism in a tertiary care hospital over a period of three years. Materials and methods: Acinetobacter species isolated from various clinical samples of a hospital were studied. Susceptibility test was performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Multidrug-resistant (MDR) strains and extended-spectrum beta-lactamases (ESBLs) were detected. Results: Out of 8,905 isolates, 490 (5.5%) were Acinetobacter species. Maximum isolates 47.1% were obtained from intensive care units (ICUs). Off the MDR isolates, 87% were from the ICUs. All the ceftazidime-resistant isolates obtained from the outpatient department (OPD) were ESBL producers (100%). Amongst the indoor wards paediatric ward showed the highest percentage of ESBL producers (71.4%). The isolation rates throughout the three years were high in the late summer and monsoon, that is, may to oct. Conclusions: Isolation of MDR Acinetobacter species continues to be significant among ICUs. It is a major challenge to control infections caused by MDR Acinetobacter spp. Therefore, the continuous surveillance of the organism is needed to understand the changing trends in epidemiology and antibiotic resistance pattern.

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