COMPARISON OF 24-HOUR I-131 THYROID UPTAKE BY GAMMA CAMERA USING HIGH ENERGY COLLIMATOR WITH STANDARD THYROID UPTAKE PROBE BASED METHOD

S. DESWAL¹, D.K. SINGH²*, D.C. BHATT^3
1Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh 226010, India
²Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh 226010, India
³Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh 226010, India
* Corresponding Author : dkpalam@gmail.com

Received : 20-06-2018     Accepted : 27-06-2018     Published : 30-06-2018
Volume : 10     Issue : 6       Pages : 1274 - 1278
Int J Microbiol Res 10.6 (2018):1274-1278
DOI : http://dx.doi.org/10.9735/0975-5276.10.6.1274-1278

Keywords : I-131, High Energy Collimator, Thyroid Uptake Probe, Gamma Camera, pertechnetate
Conflict of Interest : None declared
Acknowledgements/Funding : Author thankful to Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh 226010, India
Author Contribution : All author equally contributed

The aim and objective of this study were to the made comparison of 24-hour I-131 thyroid uptake calculated by Gamma camera-based method and thyroid uptake probe based method after administration of a diagnostic I-131 solution in patients with thyroid disease. Methods: This study group was comprised of 25 patients, out of which 10 patients were male, and 15 patients were female (Age range 20-62 yrs). In these patients had benign thyroid disorders and most of who had been referred for Thyroid evaluation before radioiodine-131 treatment. A liquid form of 131I (50μCi [1.85MBq]) was administered to the patient with adequate flushing of the vial to ensure maximum oral administration of the dose. The dose was prepared with the help of pipetting technique. Radioiodine-131 uptake was usually measured at 25 cm distance from the face of the crystal to the anterior neck or phantom and also 24 hours thyroid uptake was calculated by using a probe-based method and a camera-based method with a high-energy parallel-hole (HEGP) collimator. Gamma camera uptake calculated by two method syringe method and decay correction method for later method first correction factor derived and then applies it. Result and Discussion: Radioiodine uptake was measured by gamma camera method and thyroid uptake value was not equal of that measured by thyroid uptake probe when we use syringe method. Therefore, by applying a study specific correction factor in gamma camera uptake value and then we can equate the uptake value of probe method and gamma camera method. But when we apply correction factor in gamma camera method then the uptake values with the help of gamma camera are very close to the uptake value obtain by thyroid probe system. Conclusion: On the basis of precision in counting by thyroid uptake probe it takes the edge over gamma camera method but with the help of study specific correction factor the camera based method is a good substitute for the thyroid probe based method and the camera-based thyroid uptake method can be substituted well for the probe based method. Nuclear Medicine Centre that do not have a dedicated thyroid probe can use this method to obtain quantitative information in a single scan and thyroid uptake probe method can be replaced by gamma camera method.

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