EVALUATION OF ULTRASONOGRAPHIC GUIDED ASPIRATED SAMPLE IN EARLY DIAGNOSIS OF MUSCULOSKELETAL TUBERCULOSIS AMONG THE PATIENTS ATTENDING TERTIARY HEALTH CARE CENTRE

V. SINGH¹*, ANIL CHANDRA PHUKAN², B. BORGOHAIN^3
1Senior Resident, Department of Microbiology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, 226010, Uttar Pradesh, India
²Professor and Head, Department of Microbiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, 793012, Meghalaya, India
³Head, Department of Orthopaedics and Trauma, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, 793012, Meghalaya, India
* Corresponding Author : vikramjeet1102@gmail.com

Received : 30-05-2018     Accepted : 07-06-2018     Published : 30-06-2018
Volume : 10     Issue : 6       Pages : 1240 - 1243
Int J Microbiol Res 10.6 (2018):1240-1243
DOI : http://dx.doi.org/10.9735/0975-5276.10.6.1240-1243

Keywords : Polymerase Chain reaction, Extrapulmonary tuberculosis, Osteoarticular, USG
Conflict of Interest : None declared
Acknowledgements/Funding : Author thankful to Department of Microbiology and Department of Orthopaedics, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong Author also thankful to State Tuberculosis Society, Meghalaya, India under RNTCP, GOI for financial support for this study.
Author Contribution : All author equally contributed

Musculoskeletal tuberculosis considered as diagnostic dilemma by clinicians because diagnosis often gets delayed due to its varied presentation, false negative results on smear microscopy and less sensitivity on culture methods. The main objective was to know the effectiveness of using ultrasonographic guided aspirate sample in early diagnosis of musculoskeletal tuberculosis. Materials and Methods: In the present study, among newly suspected musculoskeletal tuberculosis total of thirty-seven clinical specimens like pus swab and ultrasonography guided (USG) pus aspiration were evaluated for microscopy, culture and molecular detection of M. tuberculosis. Results: The study reveals prevalence of 45.9% musculoskeletal tuberculosis among the clinically suspected patients. The most commonly involved sites in suspected musculoskeletal tuberculosis were hip joint (23.1%). USG guided pus comprises only 26.9% of the samples collected, however, yield of M. tuberculosis from them were 71%. PCR detected the maximum number of cases of musculoskeletal tuberculosis 17 (45.9%) followed by culture method 9 (24%) and smear microscopy 1 (2.7%). Conclusion: This observation will help guiding clinicians in effective management of musculoskeletal tuberculosis cases because delayed diagnosis and treatment in musculoskeletal TB results in poor outcome.

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