INTRAVITREAL DEXAMETHASONE IMPLANT IN THE TREATMENT OF A PATIENT WITH CYSTOID MACULAR OEDEMA SECONDARY TO LOWER BRANCH RETINAL VEIN OCCLUSION - A CASE REPORT

A. KABIESZ¹*, D. ROMANIUK², D. ÅšPIEWAK³, A. GABOREK⁴, M. NOWAK⁵, K. MICHALSKA-MAŁECKA^6
1Department of Ophthalmology, University Centre of Ophthalmology ad Oncology of Medical University of Silesia, Ceglana Street 35, 40-952 Katowice, Poland.
²Department of Ophthalmology, University Centre of Ophthalmology ad Oncology of Medical University of Silesia, Ceglana Street 35, 40-952 Katowice, Poland.
³Department of Ophthalmology, University Centre of Ophthalmology ad Oncology of Medical University of Silesia, Ceglana Street 35, 40-952 Katowice, Poland.
⁴Department of Ophthalmology, University Centre of Ophthalmology ad Oncology of Medical University of Silesia, Ceglana Street 35, 40-952 Katowice, Poland.
⁵Pathophysiology Division, Department of Pathophysiology and Endocrinology, Medical University of Silesia, Traugutta Square 2, 41-800 Zabrze, Poland.
⁶Department of Ophthalmology, University Centre of Ophthalmology ad Oncology of Medical University of Silesia, Ceglana Street 35, 40-952 Katowice, Poland.
* Corresponding Author : adam.kabiesz@gmail.com

Received : 08-07-2014     Accepted : 09-10-2014     Published : 16-10-2014
Volume : 5     Issue : 1       Pages : 63 - 67
Med Case Rep 5.1 (2014):63-67

Keywords : retinal vein occlusion, cystoids macular oedema, dexamethason, intravitreal iniection, reimplantation
Academic Editor : Dr Sung Jae Yang, Dr Athanasia Papazafiropoulou, Murat Kucukevcilioglu
Conflict of Interest : The authors declare that they have no competing interests.
Acknowledgements/Funding : We would like to give special thanks to Wanda Romaniuk, professor in Medical University of Silesia, Head of the Chair and Clinic of Ophthalmology for her guidance and help.
Author Contribution : AK, have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data. KMM, DÅš, AG, DR & MN, have been involved in drafting the manuscript and revising it critically for important intellectual co

Introduction: Purpose of this study is to present the results of reimplantation of biodegradable intravitreal implant of dexamethasone (Ozurdex®) of patient with cystoid macular oedema secondary to temporal lower branch retinal vein occlusion. This article is the first documented case report of treatment with 2 intravitreal implants of dexamethasone. Case Presentation: The patient with cystoids macular oedema secondary to temporal lower branch retinal vein occlusion. The diagnosis was based on examination of the eyes, extended by fluorescein angiography and optical coherence tomography. Implantations of Ozurdex® took place in the operating theatre, while respecting aseptic conditions and in accordance with the principles of intravitreal injections. From the onset of symptoms to the administration passed the time of 2 weeks. Patient controls were held on schedule: 2 weeks, 4 months, 7 months, 8 months and 10 months since the onset of symptoms and included measurements of visual acuity, intraocular pressure, optical coherence tomography of the retina. Before implantation as well as in postoperative period patients used topical antibiotic with an extended spectrum of action (Vigamox®). Conclusions: In the presented patient with cystoids macular oedema secondary to branch retinal vein occlusion, the use of an intravitreal biodegradable implant containing dexamethasone (Ozurdex®) resulted in improved visual acuity and reduced retinal oedema. The first implantation of a biodegradable implant containing dexamethasone resulted in partial improvement of functional and morphological condition of central retina. A six-month follow-up after reimplantation of Ozurdex® showed functional and morphological stabilisation of central retina. Ozurdex® is an effective drug in the treatment of cystoid retinal edema resulting from retinal vein occlusion.