HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY

IBRAIMOV A.I.; AKANOV A.A.; MEIMANALIEV T.S.; SHARIPOV K.O.; SMAILOVA R.D.; DOSYMBEKOVA R.

HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY

IBRAIMOV A.I.¹*, AKANOV A.A.², MEIMANALIEV T.S.³, SHARIPOV K.O.⁴, SMAILOVA R.D.⁵, DOSYMBEKOVA R.⁶
¹Kazakh National Medical University after name S.D. Asfendyarov, Tole bi str., 88, Almaty, KZ-050012, Kazakhstan.
²Institute of Balneology and Physiotherapy, Bishkek, KG-720 040, Kyrgyzstan.
³Institute of Balneology and Physiotherapy, Bishkek, KG-720 040, Kyrgyzstan.
⁴Institute of Balneology and Physiotherapy, Bishkek, KG-720 040, Kyrgyzstan.
⁵Institute of Balneology and Physiotherapy, Bishkek, KG-720 040, Kyrgyzstan.
⁶Institute of Balneology and Physiotherapy, Bishkek, KG-720 040, Kyrgyzstan.
* Corresponding Author : ibraimov_abyt@mail.ru

Received : 28-03-2014 Accepted : 21-04-2014 Published : 05-05-2014
Volume : 6 Issue : 1 Pages : 142 - 148
Genetics 6.1 (2014):142-148

Keywords : Human Chromosomal Q-Heterochromatin, Human Body Heat Conductivity, Cell Thermoregulation, Human Adaptation
Conflict of Interest : None declared
Acknowledgements/Funding : We are grateful to students of Kazakh National Medical University after name S.D. Asfendyarov for their cooperation and to Miss M. Hozhahmedova, Miss D. Meyrbek, Miss A. Naldibekova and Miss M. Vansinvina for their technical assistance in this work

Cite - MLA : IBRAIMOV A.I., et al "HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY." International Journal of Genetics 6.1 (2014):142-148.

Cite - APA : IBRAIMOV A.I., AKANOV A.A., MEIMANALIEV T.S., SHARIPOV K.O., SMAILOVA R.D., DOSYMBEKOVA R. (2014). HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY. International Journal of Genetics, 6 (1), 142-148.

Cite - Chicago : IBRAIMOV A.I., AKANOV A.A., MEIMANALIEV T.S., SHARIPOV K.O., SMAILOVA R.D., and DOSYMBEKOVA R. "HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY." International Journal of Genetics 6, no. 1 (2014):142-148.

Copyright : © 2014, IBRAIMOV A.I., et al, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

It is found that approximately 15-20% of non-coding part of human DNA is constitutive heterochromatin. There are two types of constitutive heterochromatin: C- and Q-heterochromatin. C-heterochromatin regions (C-HRs) are found in the genome of all higher eukaryotes, while Q-heterochromatin regions (Q-HRs) are only in the genome of three higher primates (Homo sapiens, Pan troglodytes and Gorilla gorilla). Human chromosomes possess both types of constitutive heterochromatin. In man C-heterochromatin is present in all his chromosomes, varying mainly in size, while Q-heterochromatin can only be detected on seven autosomes and the Y-chromosome. In this case individuals in a population differ from each other on the number, location, size and intensity of staining (fluorescence) of chromosomal Q-HRs. However, the question of possible biological role of chromosomal Q-HRs in human life remains open. A hypothesis that amount of Q-HRs in genome is possibly connected with human body thermal conductivity (BHC) has been proved. Results obtained show that individuals in population truly differ from each other in BHC and its level depends on the amount of chromosomal Q-HRs in human genome. The question of place and possible role of human BHC in norm and pathology is also being discussed.

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