EFFECT OF CINNAMOMUM CAMPHORA ON HUMAN SPERM MOTILITY AND SPERM VIABILITY

Jadhav M.V.¹, Sharma R.C.²*, Rathore Mansee³, Gangawane A.K.^4
1School of Biomedical Science, Department of Biotechnology, M.G.M Institute of Health Sciences, Sec- 18, Kamothe, Navi Mumbai
²Department of Physiology, M.G.M Medical College, Sec-18, Kamothe, Navi Mumbai
³School of Biomedical Science, Department of Biotechnology, M.G.M Institute of Health Sciences, Sec- 18, Kamothe, Navi Mumbai
⁴School of Biomedical Science, Department of Biotechnology, M.G.M Institute of Health Sciences, Sec- 18, Kamothe, Navi Mumbai
* Corresponding Author : drsharmax@gmail.com

Received : -     Accepted : -     Published : 15-06-2010
Volume : 1     Issue : 1       Pages : 1 - 10
J Clin Res Lett 1.1 (2010):1-10
DOI : http://dx.doi.org/10.9735/0976-7061.1.1.1-10

Keywords : Sperm motility, camphor, mitochondria and fertilization
Conflict of Interest : None declared
Acknowledgements/Funding : This research project was supported by MGMIHS and special thanks to the Director Dr. S. N. Kadam.

Sperm motility is a crucial part of examination for studying the effect of any compound. On microscopic examination, sperms look like a swimming tadpole. Each sperm structure is composed of a head which contains the genetic material of father in its nucleus part, a tail which lashes back and forth to propel sperm along, and a midpiece which has mitochondria (power house of sperm) which provide energy for sperm motion. The presences of sugar fructose produced by seminal vesicles provide energy for sperm motility. An alkaline pH of sperm is an important characteristic. Camphor, from the above study is regarded as poisonous if ingested in large doses, it acts as a contraceptive agent, an abortifacient, as suppressor of sperm motility reducing its capacity to fertilize in rats. On other hand, it has several health benefits. In this study of effect of camphor on human sperm motility and its viability, a decrease in sperm motility and sperm viability investigated with increased concentration of camphor solution. It may be due decrease in fructose levels, or denaturation of proteins, cholesterol which are indirectly connected with energy source for sperm motility. Thus, it can be indicated that there is a positive relation between Camphor and sperm parameters. Hence, camphor treated samples shows descent in sperm motility count which counts for decreasing effectiveness for fertilization and thus acts as a contraceptive.

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