SEQUENCE ALIGNMENT OF EXTRA CHROMOSOMAL DEOXYRIBOSENUCLEIC ACID BASE PAIRS OF BACTERIA AND PLANT: POSSIBLE MECHANISM OF GENOME REARRANGEMENTS

Amruta Samal¹, Gopala Rao T.V.²*
¹Department of Biotechnology, G.I.E.T., Gunupur – 765022, Orissa.
²Department of Biotechnology, G.I.E.T., Gunupur – 765022, Orissa.
* Corresponding Author : gopalraotv@yahoo.com

Received : -     Accepted : -     Published : 21-12-2009
Volume : 1     Issue : 2       Pages : 93 - 94
Int J Bioinformatics Res 1.2 (2009):93-94
DOI : http://dx.doi.org/10.9735/0975-3087.1.2.93-94

Keywords : sequence alignment, plastid, plasmid, genome, base pair rearrangements
Conflict of Interest : None declared

Computer generated sequence alignment became a conventional tool in bioinformatics. SIM is one of the methods for determining similarity between two sequences through a pair-wise sequence alignment. However, most of the conventional tools lack the ability of incorporating biological properties into the alignment result which often leads to incorrect alignment. In this paper, we used a pair-wise alignment system called SIM that incorporates biological properties into the algorithm so that it can suggest an appropriate sequence alignment based on the given nucleotide base pairs. SIM indicated nucleotide sequences alignments and suggested massive rearrangements of extra chromosomal, which can be extrapolated to total genome rearrangements.

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