YADAV K.S.1*, SMITA PATIL2, SHARMILA PATIL3, MANJYOT GAUTAM4, BHUTEY A.K.5
1Department of Biochemistry and Medicine
2Department of Biochemistry and Medicine
3Department of Biochemistry and Medicine
4Pad. Dr. PDM Medical College, Amarawati-603, India
5Padmashree Dr. D.Y. Patil Medical College, Hospital & Research Centre, Navi Mumbai-706 and Department of Biochemistry
* Corresponding Author : ksy_rahul@rediffmail.com
Received : 23-06-2011 Accepted : 03-10-2011 Published : 15-12-2011
Volume : 2 Issue : 1 Pages : 15 - 19
J Biotechnol Lett 2.1 (2011):15-19
DOI : http://dx.doi.org/10.9735/0976-7045.2.1.15-19
Conflict of Interest : None declared
Diabetes is a disease characterized by chronic hyperglycemia and several musculoskeletal disorders associates with patients of diabetic mellitus. Some are because of the disease process, others have a higher incidence in those with diabetes, and yet others are likely associated with common etiologies. The objective of the present study is to document the association of cutaneous manifestations and diabetes. Total 90 type I & II diabetic patients were studied for abnormal glucose metabolism and cutaneous manifestations with respect to infections, neuropathy, nephropathy and retinopathy. Out of 90, four percent were type I and Ninety- six percent of patients were type II diabetes. 63 patients were present cutaneous manifestations out of these 49 females (77.78%) and 14 males (22.22%). Infections and other ddermatopathy (76%) were the commonest manifestations. Diabetic retinopathy (13%) and nephropathy (11%) Hypertension (49.20%), Neuropathy (4.76%) and Coronary Disease (12.69 %) were reported. Cutaneous manifestations are quite common in type II diabetes mellitus and patients presents with multiple cutaneous manifestations, should be evaluated for systemic complications.
[1] King H., Aubert R.E., Herman W.H. (1998)
Diabetes Care, 21:1414-31.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[2] Wild S., Roglic G., Green A., Sicree R., King H.
(2004) Diabetes Care, 27: 1047-1053.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[3] Vishwanathan M., Ram, et al. (1997)
Diabetologia, 40[2]; 232-237
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[4] Urbach K., Lentz J.W. (1965) Arch
DermatolSyphilol., 52: 301- 304.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[5] Perez M.I., Kohn S.R. (1994) J Am
AcadDermatol., 30[4]:519-31.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[6] Romano G., Moretti G., Di Benedetto A., Giofre
C., Di Cesare E., Russo G., (1998) Diabetes
Res ClinPract., 39:101–6.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[7] Pastras T., Beerman H. (1964) Am Med J
1964; 247: 563- 566.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[8] Report of WHO Expert Committee on the
diagnosis and Classification of Diabetes
Mellitus (1997) Diabetes Care, 20:1183-97.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[9] Mahajan S., Koranne R.V., Sharma S.K.
(2003) Indian J DermatolVenereolLeprol.,
69:105–8.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[10] Dogra S., Kumar B., Bhansali A., Chakrabarty
A. (2002) Int J Dermatol., 41: 647- 651.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[11] Bhat Y.J., Gupta V., Kudyar R.P. (2006) Int J
DiabDevCtries., 26: 152- 15.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[12] Schemer A., Bergiman R., Linn S., Kantor Y.,
Friedman - Birnbaum R. (1998) Int J Dermatol.,
37: 113- 115.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[13] Brownlee M., Vlassara H., Kooney A., et al.
(1986) Science, 232: 1629-32.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus