Phospho-onco-proteomics

Gomase V.S.; Shyamkumar Krishnan

doi:http://dx.doi.org/10.9735/0975-2862.1.1.6-15

Phospho-onco-proteomics

Gomase V.S.¹*, Shyamkumar Krishnan²
¹Department of Bioinformatics, Padmashree Dr. D.Y. Patil University, Navi Mumbai, 400614, India
²Department of Bioinformatics, Padmashree Dr. D.Y. Patil University, Navi Mumbai, 400614, India
* Corresponding Author : virusgene1@yahoo.co.in

Received : - Accepted : - Published : 15-06-2009
Volume : 1 Issue : 1 Pages : 6 - 15
Genetics 1.1 (2009):6-15
DOI : http://dx.doi.org/10.9735/0975-2862.1.1.6-15

Keywords : Phosphoproteomics, Phosphorylation, Analytical technologies, transcriptomics
Conflict of Interest : None declared

Cite - MLA : Gomase V.S. and Shyamkumar Krishnan "Phospho-onco-proteomics." International Journal of Genetics 1.1 (2009):6-15. http://dx.doi.org/10.9735/0975-2862.1.1.6-15

Cite - APA : Gomase V.S., Shyamkumar Krishnan (2009). Phospho-onco-proteomics. International Journal of Genetics, 1 (1), 6-15. http://dx.doi.org/10.9735/0975-2862.1.1.6-15

Cite - Chicago : Gomase V.S. and Shyamkumar Krishnan "Phospho-onco-proteomics." International Journal of Genetics 1, no. 1 (2009):6-15. http://dx.doi.org/10.9735/0975-2862.1.1.6-15

Copyright : © 2009, Gomase V.S. and Shyamkumar Krishnan, Published by Bioinfo Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Phosphoproteomics is the global analysis of protein phosphorylation, holds great promise for the discovery of cell signaling events that link changes in dynamics of protein phosphorylation to the progression of various diseases, particularly cancer and diabetes. Proteomic research first came for research with the introduction of two-dimensional gel electrophoresis. Proteomics has been increasingly applied to oncology research with the widespread introduction of mass spectrometry and protein-chip. Applying proteomics to foster an improved understanding of cancer pathogenesis develop new tumor biomarkers for diagnosis, and early detection using proteomic portrait of samples. The study of Phospho-onco-proteomics provides a better understanding of cancer diagnosis.

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