EFFECT OF ACTINOMYCIN ON THE DOMINANT LETHAL MUTATION OF Drosophila melanogaster MEIGEN

KABIR M.A.^1
1Department of Biology, Holy Land College, Uttar Balubari, Dinajpur, 5200, Bangladesh.

Received : 29-03-2013     Accepted : 18-07-2013     Published : 06-08-2013
Volume : 1     Issue : 1       Pages : 10 - 12
World Res J Med Sci 1.1 (2013):10-12

Effects of Actinomycin-D (ACM-D) for dominant lethal mutations (DLM) were studied on Drosophila melanogaster. Three different doses of this actinomycin antibiotic were used for the experimental purposes. Control line was set up to compared with the findings with the treated line. Results were pooled out from three successive generations of fruit fly F₁, F₂ and F₃. It was observed that actinomycin in all its experimentally used doses induced the dominant lethal mutations. No significant differences were observed between the generations except F₁ and F₂ with F₃ recovered from 3 ml doses. Significant differences were found among flies in all the generations.