Niranjan Sutar1*, Ranju Garai2, Uma Shankar Sharma3, Umesh Kumar Sharma4, Amit jaiswal5
1Department of Pharmacy, Sir Madanlal Group of Institution-206001, India
2Department of Pharmacy, Sir Madanlal Group of Institution-206001, India
3Department of Pharmacy, Sir Madanlal Group of Institution-206001, India
4Department of Pharmacy, Sir Madanlal Group of Institution-206001, India
5Department of Pharmacy, Sir Madanlal Group of Institution-206001, India
* Corresponding Author : niranjansutar77@rediffmail.com
Received : - Accepted : - Published : 21-12-2010
Volume : 2 Issue : 2 Pages : 1 - 3
Int J Parasitol Res 2.2 (2010):1-3
DOI : http://dx.doi.org/10.9735/0975-3702.2.2.1-3
Keywords : Anthelmintic Activity, Platycladus Orieantalis, Pheretima posthuma.
Conflict of Interest : None declared
Acknowledgements/Funding : The authors are thankful to Mr.Vivek Yadav,
Chairmen,Sir Madanlal Group of Institutions,
Etawah (UP) for providing necessary facilities
and cooperation during this research work
Ethanol extract from the leaves of Platycladus orientaliswere investigated for their anthelmintic activity against Pheretima posthuma. Three concentrations (1%, 2.5% and 5%) of extract were studied in activity, which involved the determination of time of paralysis and death of the worm. The extract exhibited significant dose dependent anthelmintic activity. Piperazine citrate in same concentration as that of extract was included as standard reference and distilled water as control. The anthelmintic activity of ethanol extract of Platycladus orientalishas therefore been demonstrated for the first time.
[1] Bundy D. A. (1994) Trans Royal Soc Trop
Med Hyg, 8: 259-261.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[2] Tagbota S., Townson S. (2001) Adv
Parasitol, 50:199-205
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[3] Sondhi S.M., Shahu R., Magan Archana.
(1994) Indian Drugs, 31(7): 317-320
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[4] Kirtikar K.R. and Basu B.D. (1999) Indian
Medicinal Plants, Allahabad, Vol.-II, 856
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[5] Asima C., Satyesh C.P. (1995) the Treatise
on Indian Medicinal Plant. Editors,
Publication and Information Directorate,
New Delhi, Vol.6., 149.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[6] Kokate C.K. (1999) Practical
Pharmacognosy, 4th edn, Vallabha
Prakashan, New Delhi, 149-156.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[7] Khandelwal K.R. (2000) Practical
Pharmacognosy Technique and
Experiments, 2nd edn, Nirali Prakashan,
Pune, 149-56
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[8] Vidyarthi R.D. (1977) A Textbook of
Zoology, 14th edn, Chand and Co.
Press,New Delhi,329-31
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[9] Thorn G.W. (1977) Harrison’s Principles of
Internal Medicine, Mc Grew Hill, New
York, 1088-90
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[10] Vigar Z. (1984) Atlas of Medical
Parasitology, 2nd edn.,Publishing
House,Singapore,216-18
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[11] Ajaiyeoba E.O., Onocha P.A., Olarenwaju
O.T. (2001) Pharm Biol, 39: 217-20
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[12] Bate-Smith E.C. (1962) J Soc Bot, 58: 95-
103.
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[13] Martin R.J. (1997) Vet. J., 154:11-34
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus
[14] Mali R.G., Wadekar R.R. (2008) Indian J
Pharm.Sci, 70: 131-133
» CrossRef » Google Scholar » PubMed » DOAJ » CAS » Scopus